SCHEMBL5020960

SCHEMBL5020960

CCCCCCCCCNS(=O)(=O)c1ccccc1

nearest known ligand 0.82

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.82
LMNA P02545 2/20 0.82
PKM P14618 2/20 0.82
KDM4E B2RXH2 1/20 0.82
SMN1; SMN2 Q16637 1/20 0.82
TSHR P16473 1/20 0.71
EPHX2 P34913 1/20 0.68
TBXA2R P21731 1/20 0.66
MAPK1 P28482 2/20 0.63
RECQL P46063 1/20 0.62
CA12 O43570 1/20 0.59
CA9 Q16790 1/20 0.59
HTT P42858 1/20 0.57
MEN1 O00255 1/20 0.56
KMT2A Q03164 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL578633 1.00 ALDH1A1 (0.82) ALDH1A1LMNAPKMKDM4ESMN1; SMN2
SCHEMBL578832 1.00 ALDH1A1 (0.82) ALDH1A1LMNAPKMKDM4ESMN1; SMN2
SCHEMBL578728 1.00 ALDH1A1 (0.82) ALDH1A1LMNAPKMKDM4ESMN1; SMN2
SCHEMBL579136 1.00 ALDH1A1 (0.82) ALDH1A1LMNAPKMKDM4ESMN1; SMN2
SCHEMBL1279062 1.00 ALDH1A1 (0.82) ALDH1A1LMNAPKMKDM4ESMN1; SMN2
SCHEMBL633906 1.00 ALDH1A1 (0.82) ALDH1A1LMNAPKMKDM4ESMN1; SMN2
SCHEMBL366844 0.98 ALDH1A1 (0.79) ALDH1A1LMNAPKMKDM4ESMN1; SMN2
Bicarbonate SCHEMBL9492528 0.95 ALDH1A1 (0.74) ALDH1A1LMNAPKMKDM4ESMN1; SMN2
Trimethylammonium SCHEMBL27862582 0.95 ALDH1A1 (0.74) ALDH1A1LMNAPKMKDM4ESMN1; SMN2
Bicarbonate SCHEMBL9491178 0.95 ALDH1A1 (0.74) ALDH1A1LMNAPKMKDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996013372-A2 BUILD MATERIAL FOR FORMING A THREE DIMENSIONAL ARTICLE BPM TECHNOLOGY, INC. (US) 1996-05-09 WO claimed
US-4820346-A Ink jet printer ink HOWTEK, INC. (US) 1989-04-11 US claimed
US-8846710-B2 Method of preferentially inducing the biosynthesis of interferon 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-09-30 US disclosed
US-8846710-B2 Method of preferentially inducing the biosynthesis of interferon 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-09-30 US disclosed
US-8178677-B2 Hydroxyalkyl substituted imidazoquinolines 3M INNOVATIVE PROPERTIES COMPANY (US) 2012-05-15 US disclosed
US-8178677-B2 Hydroxyalkyl substituted imidazoquinolines 3M INNOVATIVE PROPERTIES COMPANY (US) 2012-05-15 US disclosed
US-20090029988-A1 Hydroxyalkyl Substituted Imidazoquinolines COLEY PHARMACEUTICAL GROP, INC. (US) 2009-01-29 US disclosed
US-20090029988-A1 Hydroxyalkyl Substituted Imidazoquinolines COLEY PHARMACEUTICAL GROP, INC. (US) 2009-01-29 US disclosed
US-20090030031-A1 Method of Preferentially Inducing the Biosynthesis of Interferon COLEY PHARMACEUTICAL GROUP, INC. (US) 2009-01-29 US disclosed
US-20090030031-A1 Method of Preferentially Inducing the Biosynthesis of Interferon COLEY PHARMACEUTICAL GROUP, INC. (US) 2009-01-29 US disclosed
US-5969971-A Apparatus and method for thermal normalization in three-dimensional article manufacturing BPM TECHNOLOGY, INC. (US) 1999-10-19 US disclosed
WO-1996012607-A1 APPARATUS AND METHOD FOR THERMAL NORMALIZATION IN THREE-DIMENSIONAL ARTICLE MANUFACTURING BPM TECHNOLOGY, INC. (US) 1996-05-02 WO disclosed
EP-0656040-A1 PRINTING INKS AND METHOD OF INK JET PRINTING THE GENERAL ELECTRIC COMPANY, p.l.c. (GB) 1995-06-07 EP disclosed
EP-0656039-A1 IONOMER BASED HOT-MELT INKS THE GENERAL ELECTRIC COMPANY, p.l.c. (GB) 1995-06-07 EP disclosed
US-5385957-A Adhere to substrates, yield images with good flexibility and smear resistance VIDEOJET SYSTEMS INTERNATIONAL, INC. (US) 1995-01-31 US disclosed
US-5298062-A Printing VIDEOJET SYSTEMS INTERNATIONAL, INC. (US) 1994-03-29 US disclosed
WO-1994004618-A1 PRINTING INKS AND METHOD OF INK JET PRINTING THE GENERAL ELECTRIC COMPANY PLC. (GB) 1994-03-03 WO disclosed
WO-1994004619-A1 IONOMER BASED HOT-MELT INKS THE GENERAL ELECTRIC COMPANY PLC (GB) 1994-03-03 WO disclosed
US-4820346-A Ink jet printer ink HOWTEK, INC. (US) 1989-04-11 US disclosed
US-4713489-A Preparation of N-substituted arylsulfonamides AKZO AMERICA INC. (US) 1987-12-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090030031-A1 Method of Preferentially Inducing the Biosynthesis of Interferon IFNG, IFNAR1, EIF2AK2 ALDH1A1 1275/4885LMNA 4342/4885PKM 3556/4885
US-20090029988-A1 Hydroxyalkyl Substituted Imidazoquinolines IFNG, IRF3, IFNAR1 ALDH1A1 989/4885LMNA 3293/4885PKM 3668/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.