Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18701256 | 0.86 | MAPT (0.45) | LMNAMAPTHTTSMN1; SMN2KMT2A | |
| SCHEMBL10460355 | 0.84 | TSHR (0.47) | LMNAMAPTHTTSMN1; SMN2KMT2A | |
| SCHEMBL29868310 | 0.81 | TSHR (0.45) | LMNAMAPTHTTSMN1; SMN2KMT2A | |
| SCHEMBL18701285 | 0.80 | MAPT (0.41) | LMNAMAPTHTTSMN1; SMN2KMT2A | |
| SCHEMBL1376897 | 0.78 | KMT2A (0.51) | LMNASMN1; SMN2KMT2ACDK8ACVR1 | |
| Diphencyprone SCHEMBL105663 | 0.75 | HTT (1.00) | LMNAMAPTHTTKMT2AGAA | |
| SCHEMBL13961695 | 0.75 | PDGFRA (0.49) | LMNAMAPTHTTSMN1; SMN2KMT2A | |
| SCHEMBL29634190 | 0.72 | KMT2A (0.54) | LMNAMAPTHTTSMN1; SMN2KMT2A | |
| SCHEMBL26168119 | 0.72 | KMT2A (0.54) | LMNAMAPTHTTSMN1; SMN2KMT2A | |
| SCHEMBL18701282 | 0.72 | MAPT (0.39) | LMNAMAPTHTTSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4235619-A | USING 3-PHENYL-4(1H)-PYRIDONES OR PYRIDINETHIONES | ELI LILLY AND COMPANY (US) | 1980-11-25 | — | — | US | disclosed |
| US-4152136-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1979-05-01 | — | — | US | disclosed |