Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRA | P16234 | 1/20 | 0.49 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.49 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.44 |
| ▸ | LIPE | Q05469 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.38 |
| ▸ | KCNA3 | P22001 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1522614 | 0.76 | ALDH1A1 (0.57) | PDGFRAMAPK8CDK5CLK4LMNA | |
| SCHEMBL11429710 | 0.75 | LMNA (0.58) | PDGFRAMAPK8CDK5CLK4LMNA | |
| SCHEMBL18701256 | 0.74 | MAPT (0.45) | LMNAMAPTHTTKMT2ASMN1; SMN2 | |
| SCHEMBL18701285 | 0.72 | MAPT (0.41) | LMNAMAPTHTTKMT2ASMN1; SMN2 | |
| SCHEMBL1522731 | 0.72 | PDGFRA (0.40) | PDGFRAMAPK8CDK5CLK4ERAP1 | |
| SCHEMBL14323101 | 0.72 | PDGFRA (0.53) | PDGFRAMAPK8CDK5CLK4ERAP1 | |
| SCHEMBL1376897 | 0.70 | KMT2A (0.51) | LMNAKMT2ASMN1; SMN2CDK8ACVR1 | |
| SCHEMBL18701282 | 0.69 | MAPT (0.39) | LMNAMAPTHTTKMT2ASMN1; SMN2 | |
| SCHEMBL1400093 | 0.69 | LIPE (0.31) | LIPECYP1A2 | |
| SCHEMBL10460355 | 0.69 | TSHR (0.47) | LIPECYP1A2LMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7479489-B2 | Heterocyclic antiviral compounds | ROCHE PALO ALTO LLC (US) | 2009-01-20 | — | — | US | disclosed |