Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | TYMP | P19971 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18392174 | 0.93 | HTT (0.88) | HTTMAPTLMNAALDH1A1HDAC4 | |
| SCHEMBL26201011 | 0.84 | LMNA (0.71) | HTTMAPTLMNAALDH1A1HDAC4 | |
| SCHEMBL19397826 | 0.83 | MAPT (0.68) | HTTMAPTLMNAALDH1A1HPGD | |
| Diphencyprone SCHEMBL11320515 | 0.83 | LMNA (0.68) | HTTMAPTLMNAALDH1A1HPGD | |
| SCHEMBL24625400 | 0.79 | MAPT (0.65) | HTTMAPTLMNAALDH1A1HPGD | |
| SCHEMBL12432444 | 0.79 | MAPT (0.65) | HTTMAPTLMNAALDH1A1HDAC4 | |
| SCHEMBL24625466 | 0.79 | HTT (0.65) | HTTMAPTLMNAALDH1A1HDAC4 | |
| SCHEMBL10967156 | 0.79 | LMNA (0.62) | HTTMAPTLMNAALDH1A1HDAC4 | |
| SCHEMBL216526 | 0.78 | ALDH1A1 (0.67) | HTTMAPTLMNAALDH1A1HPGD | |
| SCHEMBL11585918 | 0.77 | LMNA (0.61) | HTTMAPTLMNACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1616 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260138973-A1 | SUBSTITUTED PYRIDINES FOR USE IN TREATING OR PREVENTING INFLAMMATORY DISEASES OR DISEASES ASSOCIATED WITH AN UNDESIRABLE IMMUNE RESPONSE | SITRYX THERAPEUTICS LTD (GB) | 2026-05-21 | — | — | US | claimed |
| US-20260137680-A1 | NOVEL COMPOUNDS | SITRYX THERAPEUTICS LTD (GB) | 2026-05-21 | — | — | US | claimed |
| US-20260085061-A1 | PHTHALAZINE DERIVATIVES AS PYRUVATE KINASE MODULATORS | SITRYX THERAPEUTICS LIMITED (GB) | 2026-03-26 | — | — | US | claimed |
| EP-4634167-A1 | SUBSTITUTED PYRIDINES FOR USE IN TREATING OR PREVENTING INFLAMMATORY DISEASES OR DISEASES ASSOCIATED WITH AN UNDESIRABLE IMMUNE RESPONSE | Sitryx Therapeutics Limited (GB) | 2025-10-22 | — | — | EP | claimed |
| EP-4612132-A1 | PHTHALAZINE DERIVATIVES AS PYRUVATE KINASE MODULATORS | Sitryx Therapeutics Limited (GB) | 2025-09-10 | — | — | EP | claimed |
| CN-119930671-A | 1-Indenone derivative, preparation method and application thereof | 西华大学 | 2025-05-06 | — | — | CN | claimed |
| EP-4543875-A1 | OXADIAZOLE DERIVATIVES, PREPARATION PROCESS THEREOF AND THEIR USE IN TREATING INFLAMMATORY DISEASES | Sitryx Therapeutics Limited (GB) | 2025-04-30 | — | — | EP | claimed |
| US-20250127746-A1 | TOPICAL CONTACT SENSITIZERS TO TREAT CANCER | SQUAREX PHARMACEUTICAL CORP (US) | 2025-04-24 | — | — | US | claimed |
| EP-4536236-A2 | METHODS OF MODULATING ATXN2 EXPRESSION | University of Utah Research Foundation (US) | 2025-04-16 | — | — | EP | claimed |
| WO-2025064646-A1 | COMPOSITIONS AND METHODS FOR WOUND HEALING AND HAIR GROWTH USING POLYELECTROLYTE COMPLEX (PEC) FILMS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2025-03-27 | — | — | WO | claimed |
| US-6117223-A | Hot melt inks containing polyketones | XEROX CORPORATION (US) | 2000-09-12 | — | — | US | claimed |
| US-6063399-A | BLEND OF (METH)ACRYLATE COPOLYMER AND PLASTICIZER | ROEHM GMBH CHEMISCHE FABRIK (DE) | 2000-05-16 | — | — | US | claimed |
| US-5846559-A | Skin patch for use in contact immunotherapy | HOPP ROBERT B (US) | 1998-12-08 | — | — | US | claimed |
| US-5663030-A | A PHENYL OR NORBORNANE DERIVATIVE AS AN ADDITIVE TO REDUCE HEAT AND ENERGY REQUIRED TO FUSE THE TONER AND TO REDUCE JAMMING OF THE EQUIPMENT | XEROX CORPORATION (US) | 1997-09-02 | — | — | US | claimed |
| WO-1996032142-A1 | SKIN PATCH FOR USE IN CONTACT IMMUNOTHERAPY | HOPP ROBERT B (US) | 1996-10-17 | — | — | WO | claimed |
| US-4985464-A | Drug compositions for local treatment of alopecia areata | HAPPLE RUDOLF (DE) | 1991-01-15 | — | — | US | claimed |
| EP-0062157-B1 | MEDICINAL PREPARATION FOR THE LOCAL TREATMENT OF ALOPECIA AREATA | Happle, Rudolf, Prof. Dr.med. (DE) | 1984-06-27 | — | — | EP | claimed |
| EP-0062157-A1 | Medicinal preparation for the local treatment of alopecia areata | Happle, Rudolf, Prof. Dr.med. (DE) | 1982-10-13 | — | — | EP | claimed |
| US-4199021-A | Thermal energy storage apparatus | JOHNSON CONTROLS, INC. (US) | 1980-04-22 | — | — | US | claimed |
| US-4128422-A | Cyclopropenone vesicular imaging composition, element and process | EASTMAN KODAK COMPANY (US) | 1978-12-05 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260085061-A1 | PHTHALAZINE DERIVATIVES AS PYRUVATE KINASE MODULATORS | PDK1, PDK2, PDK4 | HTT 4159/4885MAPT 3687/4885LMNA 2450/4885 |
| US-20260137680-A1 | NOVEL COMPOUNDS | CCR1, CCR4, CCR3 | HTT 2556/4885MAPT 4412/4885LMNA 2211/4885 |
| US-20260138973-A1 | SUBSTITUTED PYRIDINES FOR USE IN TREATING OR PREVENTING INFLAMMATORY DISEASES OR DISEASES ASSOCIATED WITH AN UNDESIRABLE IMMUNE RESPONSE | CCR1, CCR2, CBR1 | HTT 3453/4885MAPT 4800/4885LMNA 2789/4885 |
| US-20250127746-A1 | TOPICAL CONTACT SENSITIZERS TO TREAT CANCER | DECR2, DECR1, CYSLTR2 | HTT 4691/4885MAPT 3989/4885LMNA 4065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.