SCHEMBL1142976

SCHEMBL1142976

CC(C)CCCCCCC(=O)COCC1CCCC1

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SPHK1 Q9NYA1 6/20 0.36
KDM4C Q9H3R0 2/20 0.34
KDM4A O75164 1/20 0.34
PHF8 Q9UPP1 1/20 0.34
KDM2A Q9Y2K7 1/20 0.34
GBA1 P04062 2/20 0.33
UGCG Q16739 2/20 0.33
GBA2 Q9HCG7 2/20 0.33
LMNA P02545 1/20 0.33
NAAA Q02083 2/20 0.33
SLC1A3 P43003 1/20 0.32
SLC1A2 P43004 1/20 0.32
SLC1A1 P43005 1/20 0.32
CNR1 P21554 1/20 0.32
CNR2 P34972 1/20 0.32
SPHK2 Q9NRA0 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1142944 1.00 SPHK1 (0.36) SPHK1KDM4CKDM4APHF8KDM2A
SCHEMBL1143108 0.99 SPHK1 (0.38) SPHK1KDM4CKDM4APHF8KDM2A
SCHEMBL1143205 0.99 SPHK1 (0.38) SPHK1KDM4CKDM4APHF8KDM2A
SCHEMBL1142768 0.88 LMNA (0.37) SPHK1GBA1UGCGGBA2LMNA
SCHEMBL1143369 0.86 LMNA (0.39) SPHK1GBA1UGCGGBA2LMNA
SCHEMBL2323420 0.83 NAAA (0.49) SPHK1NAAA
SCHEMBL1142598 0.83 NAAA (0.49) SPHK1NAAA
SCHEMBL2343251 0.83 NAAA (0.49) SPHK1NAAA
SCHEMBL1143578 0.82 NAAA (0.50) SPHK1LMNANAAA
SCHEMBL17061000 0.82 NAAA (0.50) SPHK1LMNANAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3204159-B1 PROCESS FOR PREPARING SPHERICAL POLYMERIZATION CATALYST COMPONENTS FOR USE IN OLEFIN POLYMERIZATIONS GRACE W R & CO (US) 2020-12-16 EP disclosed
EP-2701843-B1 EMULSION PROCESS FOR IMPROVED LARGE SPHERICAL POLYPROPYLENE CATALYSTS W R GRACE & CO -CONN (US) 2017-11-29 EP disclosed
US-9714302-B2 Process for preparing spherical polymerization catalyst components for use in olefin polymerizations W. R. Grace & Co.—Conn. (US) 2017-07-25 US disclosed
US-9403924-B2 Process of production of large and spherical polymerization catalyst and use of same in olefin polymerizations BASF CORPORATION (US) 2016-08-02 US disclosed
US-20160102156-A1 PROCESS FOR PREPARING SPHERICAL POLYMERIZATION CATALYST COMPONENTS FOR USE IN OLEFIN POLYMERIZATIONS W. R. GRACE & CO.-CONN. 2016-04-14 US disclosed
US-20150361194-A1 PROCESS OF PRODUCTION OF LARGE AND SPHERICAL POLYMERIZATION CATALYST AND USE OF SAME IN OLEFIN POLYMERIZATIONS W. R. GRACE & CO.-CONN. 2015-12-17 US disclosed
EP-2440589-B1 INTERNAL DONOR FOR OLEFIN POLYMERIZATION CATALYSTS BASF CORP (US) 2015-09-09 EP disclosed
US-8569195-B2 Internal and external donor compounds for olefin polymerization catalysts II BASF CORPORATION (US) 2013-10-29 US disclosed
US-20120277090-A1 EMULSION PROCESS FOR IMPROVED LARGE SPHERICAL POLYPROPYLENE CATALYSTS BASF CORPORATION (US) 2012-11-01 US disclosed
US-20110207901-A1 INTERNAL AND EXTERNAL DONOR COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS II BASF CATALYSTS LLC (US) 2011-08-25 US disclosed
US-8003559-B2 Internal donor for olefin polymerization catalysts BASF CORPORATION (US) 2011-08-23 US disclosed
US-20110034651-A1 MIXED DONOR SYSTEM FOR HIGH MELT FLOW AND HIGH ACTIVITY BASF CATALYSTS LLC (US) 2011-02-10 US disclosed
US-20090286672-A1 INTERNAL DONOR FOR OLEFIN POLYMERIZATION CATALYSTS BASF CATALYSTS LLC (US) 2009-11-19 US disclosed