Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.54 |
| ▸ | HSP90AB1 | P08238 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | TET2 | Q6N021 | 2/20 | 0.50 |
| ▸ | TET1 | Q8NFU7 | 2/20 | 0.50 |
| ▸ | KDM6B | O15054 | 1/20 | 0.50 |
| ▸ | KDM6A | O15550 | 1/20 | 0.50 |
| ▸ | TET3 | O43151 | 1/20 | 0.50 |
| ▸ | KDM4A | O75164 | 1/20 | 0.50 |
| ▸ | KDM4B | O94953 | 1/20 | 0.50 |
| ▸ | KDM5C | P41229 | 1/20 | 0.50 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.50 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.50 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.50 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.50 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL68215 | 0.83 | ALDH1A1 (0.54) | ALDH1A1LMNAALOX12KDM4EL3MBTL1 | |
| SCHEMBL29089214 | 0.83 | ALDH1A1 (0.54) | ALDH1A1LMNAALOX12KDM4EL3MBTL1 | |
| SCHEMBL30605381 | 0.83 | ALDH1A1 (0.54) | ALDH1A1LMNAALOX12KDM4EL3MBTL1 | |
| SCHEMBL744645 | 0.81 | ALDH1A1 (0.53) | ALDH1A1LMNAALOX12KDM4EL3MBTL1 | |
| SCHEMBL21816294 | 0.81 | PSMD14 (0.56) | ALDH1A1LMNAALOX12KDM4EL3MBTL1 | |
| SCHEMBL8544466 | 0.81 | ALDH1A1 (0.53) | ALDH1A1HSP90AA1HSP90AB1LMNAALOX12 | |
| SCHEMBL4602037 | 0.81 | ALDH1A1 (0.53) | ALDH1A1LMNAALOX12KDM4EL3MBTL1 | |
| SCHEMBL29046675 | 0.81 | KDM4E (0.55) | ALDH1A1HSP90AA1HSP90AB1KDM4EEGLN1 | |
| SCHEMBL14820315 | 0.79 | MEN1 (0.53) | ALDH1A1LMNAALOX12KDM4EL3MBTL1 | |
| SCHEMBL111826 | 0.78 | PARP1 (0.70) | ALDH1A1HSP90AA1LMNAALOX12KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4186201-A | ANTIALLERGIC AGENTS | RIKER LABORATORIES, INC. (US) | 1980-01-29 | — | — | US | disclosed |
| US-4147694-A | ANTIALLERGENS, ANTIHISTAMINES | RIKER LABORATORIES, INC. (US) | 1979-04-03 | — | — | US | disclosed |