SCHEMBL1142980

SCHEMBL1142980

CCCCCCCCC(=O)C1(COC)CCCC1C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 2/20 0.40
PRKCA P17252 4/20 0.36
CES2 O00748 3/20 0.33
CES1 P23141 3/20 0.33
EPHX2 P34913 1/20 0.33
DGKA P23743 1/20 0.33
PPARG P37231 3/20 0.33
PPARD Q03181 3/20 0.33
PPARA Q07869 3/20 0.33
TSHR P16473 2/20 0.33
GPR84 Q9NQS5 2/20 0.33
HDAC11 Q96DB2 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
ALDH1A1 P00352 1/20 0.33
SLC22A6 Q4U2R8 1/20 0.33
SLC22A8 Q8TCC7 1/20 0.33
TLR2 O60603 1/20 0.33
MEN1 O00255 1/20 0.33
ESR1 P03372 1/20 0.33
FABP4 P15090 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1143586 1.00 NAAA (0.40) NAAAPRKCACES2CES1EPHX2
SCHEMBL2347085 1.00 NAAA (0.40) NAAAPRKCACES2CES1EPHX2
SCHEMBL1142521 0.99 NAAA (0.38) NAAAPRKCACES2CES1EPHX2
SCHEMBL1142815 0.96 NAAA (0.42) NAAAPRKCACES2CES1
SCHEMBL1143280 0.96 NAAA (0.42) NAAAPRKCACES2CES1
SCHEMBL2491703 0.94 NAAA (0.40) NAAAPRKCACES2CES1TDP1
SCHEMBL1142551 0.94 NAAA (0.40) NAAAPRKCACES2CES1TDP1
SCHEMBL1142880 0.94 MEN1 (0.33) NAAAPRKCAMEN1KMT2A
SCHEMBL1142740 0.90 NAAA (0.35) NAAAMEN1KMT2A
SCHEMBL2686612 0.85 CDC25A (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3118226-A1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF Corporation (US) 2017-01-18 EP claimed
EP-2782938-B1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF CORP (US) 2016-08-31 EP claimed
EP-2782938-A1 HIGH ACTIVITY CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND METHOD OF USING THE SAME BASF Corporation (US) 2014-10-01 EP claimed
WO-2013077837-A1 HIGH ACTIVITY CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND METHOD OF USING THE SAME BASF CORPORATION (US) 2013-05-30 WO claimed
US-8227370-B2 High activity catalyst component for olefin polymerization and method of using the same BASF CORPORATION (US) 2012-07-24 US claimed
US-20120116031-A1 High Activity Catalyst Component for Olefin Polymerization and Method of Using the Same BASF CORPORATION (US) 2012-05-10 US claimed
EP-3204159-B1 PROCESS FOR PREPARING SPHERICAL POLYMERIZATION CATALYST COMPONENTS FOR USE IN OLEFIN POLYMERIZATIONS GRACE W R & CO (US) 2020-12-16 EP disclosed
CN-107207657-B Process for preparing spherical polymerization catalyst components for olefin polymerization 格雷斯公司 2020-03-03 CN disclosed
EP-2701843-B1 EMULSION PROCESS FOR IMPROVED LARGE SPHERICAL POLYPROPYLENE CATALYSTS W R GRACE & CO -CONN (US) 2017-11-29 EP disclosed
US-9714302-B2 Process for preparing spherical polymerization catalyst components for use in olefin polymerizations W. R. Grace & Co.—Conn. (US) 2017-07-25 US disclosed
EP-3118226-A1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF Corporation (US) 2017-01-18 EP disclosed
EP-2782938-B1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF CORP (US) 2016-08-31 EP disclosed
US-9403924-B2 Process of production of large and spherical polymerization catalyst and use of same in olefin polymerizations BASF CORPORATION (US) 2016-08-02 US disclosed
EP-2440589-A1 INTERNAL DONOR FOR OLEFIN POLYMERIZATION CATALYSTS BASF Corporation (US) 2012-04-18 EP disclosed
US-20110207901-A1 INTERNAL AND EXTERNAL DONOR COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS II BASF CATALYSTS LLC (US) 2011-08-25 US disclosed
US-8003559-B2 Internal donor for olefin polymerization catalysts BASF CORPORATION (US) 2011-08-23 US disclosed
WO-2011017283-A2 MIXED DONOR SYSTEM FOR HIGH MELT FLOW AND HIGH ACTIVITY BASF CORPORATION (US) 2011-02-10 WO disclosed
US-20110034651-A1 MIXED DONOR SYSTEM FOR HIGH MELT FLOW AND HIGH ACTIVITY BASF CATALYSTS LLC (US) 2011-02-10 US disclosed
WO-2010144079-A1 INTERNAL DONOR FOR OLEFIN POLYMERIZATION CATALYSTS BASF CATALYSTS LLC (US) 2010-12-16 WO disclosed
US-20090286672-A1 INTERNAL DONOR FOR OLEFIN POLYMERIZATION CATALYSTS BASF CATALYSTS LLC (US) 2009-11-19 US disclosed