SCHEMBL1143280

SCHEMBL1143280

CCCCCCC(=O)C1(COC)CCCCC1C

nearest known ligand 0.42

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 3/20 0.42
PRKCA P17252 5/20 0.35
CES2 O00748 3/20 0.33
CES1 P23141 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1142815 1.00 NAAA (0.42) NAAAPRKCACES2CES1
SCHEMBL2491703 0.99 NAAA (0.40) NAAAPRKCACES2CES1
SCHEMBL1142551 0.99 NAAA (0.40) NAAAPRKCACES2CES1
SCHEMBL1142980 0.96 NAAA (0.40) NAAAPRKCACES2CES1
SCHEMBL1143586 0.96 NAAA (0.40) NAAAPRKCACES2CES1
SCHEMBL2347085 0.96 NAAA (0.40) NAAAPRKCACES2CES1
SCHEMBL1142521 0.94 NAAA (0.38) NAAAPRKCACES2CES1
SCHEMBL1142740 0.94 NAAA (0.35) NAAA
SCHEMBL1142880 0.90 MEN1 (0.33) NAAAPRKCA
SCHEMBL1142573 0.89 DPP4 (0.33) NAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3118226-A1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF Corporation (US) 2017-01-18 EP claimed
EP-2782938-B1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF CORP (US) 2016-08-31 EP claimed
EP-2782938-A1 HIGH ACTIVITY CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND METHOD OF USING THE SAME BASF Corporation (US) 2014-10-01 EP claimed
WO-2013077837-A1 HIGH ACTIVITY CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND METHOD OF USING THE SAME BASF CORPORATION (US) 2013-05-30 WO claimed
US-8227370-B2 High activity catalyst component for olefin polymerization and method of using the same BASF CORPORATION (US) 2012-07-24 US claimed
US-20120116031-A1 High Activity Catalyst Component for Olefin Polymerization and Method of Using the Same BASF CORPORATION (US) 2012-05-10 US claimed
EP-3204159-B1 PROCESS FOR PREPARING SPHERICAL POLYMERIZATION CATALYST COMPONENTS FOR USE IN OLEFIN POLYMERIZATIONS GRACE W R & CO (US) 2020-12-16 EP disclosed
CN-107207657-B Process for preparing spherical polymerization catalyst components for olefin polymerization 格雷斯公司 2020-03-03 CN disclosed
EP-2701843-B1 EMULSION PROCESS FOR IMPROVED LARGE SPHERICAL POLYPROPYLENE CATALYSTS W R GRACE & CO -CONN (US) 2017-11-29 EP disclosed
US-9714302-B2 Process for preparing spherical polymerization catalyst components for use in olefin polymerizations W. R. Grace & Co.—Conn. (US) 2017-07-25 US disclosed
EP-3118226-A1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF Corporation (US) 2017-01-18 EP disclosed
EP-2782938-B1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF CORP (US) 2016-08-31 EP disclosed
US-9403924-B2 Process of production of large and spherical polymerization catalyst and use of same in olefin polymerizations BASF CORPORATION (US) 2016-08-02 US disclosed
CN-102574954-A Internal donor for olefin polymerization catalysts BASF CATALYSTS LLC 2012-07-11 CN disclosed
US-20120116031-A1 High Activity Catalyst Component for Olefin Polymerization and Method of Using the Same BASF CORPORATION (US) 2012-05-10 US disclosed
WO-2011106480-A2 INTERNAL AND EXTERNAL DONOR COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS II BASF CORPORATION (US) 2011-09-01 WO disclosed
US-20110207901-A1 INTERNAL AND EXTERNAL DONOR COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS II BASF CATALYSTS LLC (US) 2011-08-25 US disclosed
US-8003559-B2 Internal donor for olefin polymerization catalysts BASF CORPORATION (US) 2011-08-23 US disclosed
US-20110034651-A1 MIXED DONOR SYSTEM FOR HIGH MELT FLOW AND HIGH ACTIVITY BASF CATALYSTS LLC (US) 2011-02-10 US disclosed
US-20090286672-A1 INTERNAL DONOR FOR OLEFIN POLYMERIZATION CATALYSTS BASF CATALYSTS LLC (US) 2009-11-19 US disclosed