Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 3/20 | 0.40 |
| ▸ | PRKCA | P17252 | 5/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1142551 | 1.00 | NAAA (0.40) | NAAAPRKCAL3MBTL1CES2CES1 | |
| SCHEMBL1143280 | 0.99 | NAAA (0.42) | NAAAPRKCACES2CES1 | |
| SCHEMBL1142815 | 0.99 | NAAA (0.42) | NAAAPRKCACES2CES1 | |
| SCHEMBL1142521 | 0.96 | NAAA (0.38) | NAAAPRKCAL3MBTL1CES2CES1 | |
| SCHEMBL1142740 | 0.96 | NAAA (0.35) | NAAAMEN1KMT2A | |
| SCHEMBL2347085 | 0.94 | NAAA (0.40) | NAAAPRKCACES2CES1MEN1 | |
| SCHEMBL1142980 | 0.94 | NAAA (0.40) | NAAAPRKCACES2CES1MEN1 | |
| SCHEMBL1143586 | 0.94 | NAAA (0.40) | NAAAPRKCACES2CES1MEN1 | |
| SCHEMBL1142880 | 0.92 | MEN1 (0.33) | NAAAPRKCAMEN1KMT2A | |
| SCHEMBL1142573 | 0.90 | DPP4 (0.33) | NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2539375-A2 | INTERNAL AND EXTERNAL DONOR COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS II | BASF Corporation (US) | 2013-01-02 | — | — | EP | disclosed |
| WO-2011106480-A2 | INTERNAL AND EXTERNAL DONOR COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS II | BASF CORPORATION (US) | 2011-09-01 | — | — | WO | disclosed |