SCHEMBL11429985

SCHEMBL11429985

S=P([S-])(OCc1ccccc1)OCc1ccccc1.S=P([S-])(OCc1ccccc1)OCc1ccccc1.S=P([S-])(OCc1ccccc1)OCc1ccccc1.[Sb+3]

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
CA9 Q16790 2/20 0.44
CA12 O43570 1/20 0.44
IDO1 P14902 1/20 0.43
AGXT P21549 1/20 0.41
SRC P12931 1/20 0.39
CETP P11597 3/20 0.39
PDPK1 O15530 1/20 0.38
MTOR P42345 1/20 0.38
MAOB P27338 1/20 0.37
ALDH1A1 P00352 3/20 0.36
LMNA P02545 1/20 0.36
CYP1A2 P05177 1/20 0.36
PTGS1 P23219 1/20 0.36
SLC6A2 P23975 1/20 0.36
CYP2C19 P33261 1/20 0.36
PTGS2 P35354 1/20 0.36
SLC6A3 Q01959 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Zinc Ion SCHEMBL132692 0.96 TSHR (0.50) TSHRCA1CA2CA9CA12
SCHEMBL10691592 0.96 TSHR (0.50) TSHRCA1CA2CA9CA12
SCHEMBL11365126 0.84 ALDH1A1 (0.55) TSHRCA1CA2CA9CA12
SCHEMBL18279927 0.79 TSHR (0.56) TSHRCA1CA2CA9CA12
SCHEMBL3068400 0.76 TSHR (0.63) TSHRCA1CA2CA9CA12
SCHEMBL1491990 0.76 TSHR (0.63) TSHRCA1CA2CA9CA12
SCHEMBL11419361 0.76 TSHR (0.52) TSHRCA1CA2CA9CA12
SCHEMBL3068595 0.76 TSHR (0.52) TSHRCA1CA2CA9CA12
SCHEMBL8044384 0.76 TSHR (0.52) TSHRCA1CA2CA9CA12
SCHEMBL1491036 0.76 TSHR (0.52) TSHRCA1CA2CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4207204-A VANADIUM, IRON, OR NICKEL PHILLIPS PETROLEUM COMPANY (US) 1980-06-10 US claimed
US-4166806-A Cracking catalyst passivated with a crude antimony phosphorodithioate PHILLIPS PETROLEUM COMPANY (US) 1979-09-04 US claimed
US-4207204-A VANADIUM, IRON, OR NICKEL PHILLIPS PETROLEUM COMPANY (US) 1980-06-10 US disclosed
US-4166806-A Cracking catalyst passivated with a crude antimony phosphorodithioate PHILLIPS PETROLEUM COMPANY (US) 1979-09-04 US disclosed