Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD40 | P25942 | 2/20 | 0.53 |
| ▸ | CD40LG | P29965 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TYMS | P04818 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MITF | O75030 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CASP2 | P42575 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11430148 | 0.88 | KMT2A (0.58) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL11434109 | 0.86 | CD40 (0.56) | CD40CD40LGMEN1KMT2ARAB9A | |
| SCHEMBL11423038 | 0.84 | MEN1 (0.52) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL10909144 | 0.83 | ENPP2 (0.56) | CD40CD40LGKMT2AENPP2CASP6 | |
| SCHEMBL11343949 | 0.83 | ENPP2 (0.56) | ENPP2CASP6 | |
| SCHEMBL11425014 | 0.83 | CASP6 (0.57) | MEN1KMT2AENPP2MAPTPOLB | |
| SCHEMBL11436268 | 0.83 | MAPT (0.57) | CD40CD40LGMEN1KMT2ARAB9A | |
| SCHEMBL11423173 | 0.82 | CASP6 (0.53) | CD40CD40LGMEN1KMT2ARAB9A | |
| SCHEMBL11422942 | 0.82 | CD40 (0.57) | CD40CD40LGMEN1KMT2ARAB9A | |
| SCHEMBL11431130 | 0.80 | CD40 (0.66) | CD40CD40LGMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216166-A | Nitro precursors to amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |