Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11423138 | 0.93 | CYP1A2 (0.44) | KCNMA1ALDH1A1HPGDTDP1KMT2A | |
| SCHEMBL11426113 | 0.92 | KCNMA1 (0.46) | KCNMA1ALDH1A1HPGDTDP1KMT2A | |
| SCHEMBL11425646 | 0.86 | ALDH1A1 (0.42) | ALDH1A1HPGDKMT2ASTAT3MEN1 | |
| SCHEMBL11426602 | 0.85 | KCNMA1 (0.48) | KCNMA1ALDH1A1HPGDTDP1KMT2A | |
| SCHEMBL11426442 | 0.84 | KCNMA1 (0.45) | KCNMA1ALDH1A1HPGDTDP1KMT2A | |
| SCHEMBL11439176 | 0.84 | NT5E (0.45) | KCNMA1ALDH1A1HPGDTDP1STAT3 | |
| SCHEMBL11430233 | 0.83 | POLB (0.52) | ALDH1A1TDP1KMT2AMEN1GAA | |
| SCHEMBL11421980 | 0.83 | KCNMA1 (0.51) | KCNMA1ALDH1A1HPGDTDP1KMT2A | |
| SCHEMBL11425120 | 0.83 | KCNMA1 (0.51) | KCNMA1ALDH1A1HPGDTDP1KMT2A | |
| SCHEMBL11424933 | 0.82 | ALDH1A1 (0.42) | ALDH1A1HPGDHKDC1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216166-A | Nitro precursors to amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |