Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 2/20 | 0.45 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 2/20 | 0.40 |
| ▸ | CASP6 | P55212 | 2/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11431542 | 0.93 | NT5E (0.55) | NT5EKCNMA1POLBSNCAALDH1A1 | |
| SCHEMBL11438448 | 0.93 | PRMT1 (0.48) | NT5EKCNMA1POLBSNCAALDH1A1 | |
| SCHEMBL11215156 | 0.92 | NT5E (0.54) | NT5EKCNMA1POLBSNCAALDH1A1 | |
| SCHEMBL11437160 | 0.92 | KCNMA1 (0.45) | NT5EKCNMA1POLBSNCAALDH1A1 | |
| SCHEMBL11438443 | 0.88 | PRMT1 (0.56) | NT5EKCNMA1POLBSNCAALDH1A1 | |
| SCHEMBL11435464 | 0.86 | NT5E (0.50) | NT5ESNCAALDH1A1NSD2CASP6 | |
| SCHEMBL11423138 | 0.86 | CYP1A2 (0.44) | NT5EKCNMA1POLBSNCAALDH1A1 | |
| SCHEMBL11428750 | 0.85 | NT5E (0.55) | NT5EKCNMA1POLBSNCAALDH1A1 | |
| SCHEMBL11430236 | 0.84 | KCNMA1 (0.43) | KCNMA1POLBALDH1A1HPGDTDP1 | |
| SCHEMBL11424233 | 0.84 | PRMT1 (0.48) | KCNMA1POLBSNCAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216166-A | Nitro precursors to amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |