Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11434510 | 0.96 | KCNMA1 (0.54) | KCNMA1NPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL11421980 | 0.92 | KCNMA1 (0.51) | KCNMA1NPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL11436839 | 0.90 | KCNMA1 (0.52) | KCNMA1NPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL11425120 | 0.88 | KCNMA1 (0.51) | KCNMA1NPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL11433368 | 0.85 | KCNMA1 (0.51) | KCNMA1NPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL11422990 | 0.84 | KCNMA1 (0.50) | KCNMA1NPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL11433122 | 0.84 | ALDH1A1 (0.42) | KCNMA1RAB9ACYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL11438676 | 0.84 | ALDH1A1 (0.42) | KCNMA1RAB9ACYP1A2ALDH1A1GAA | |
| SCHEMBL11423371 | 0.84 | KCNMA1 (0.57) | KCNMA1NPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL11426113 | 0.83 | KCNMA1 (0.46) | KCNMA1NPC1RAB9ACYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216166-A | Nitro precursors to amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |