Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CASP6 | P55212 | 2/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.39 |
| ▸ | PLG | P00747 | 3/20 | 0.38 |
| ▸ | KLK1 | P06870 | 2/20 | 0.38 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11427487 | 0.96 | ALDH1A1 (0.42) | ALDH1A1HSD17B10CASP6CTDSP1EP300 | |
| SCHEMBL11433122 | 0.91 | ALDH1A1 (0.42) | ALDH1A1HSD17B10CASP6CTDSP1EP300 | |
| SCHEMBL11434111 | 0.88 | RAB9A (0.43) | HSD17B10CASP6CTDSP1KCNMA1PLG | |
| SCHEMBL11435627 | 0.87 | ALDH1A1 (0.42) | ALDH1A1HSD17B10CASP6CTDSP1EP300 | |
| SCHEMBL11425760 | 0.84 | PLG (0.44) | ALDH1A1HSD17B10CASP6KCNMA1PLG | |
| SCHEMBL11430424 | 0.84 | KCNMA1 (0.54) | ALDH1A1KCNMA1POLBCYP1A2GAA | |
| SCHEMBL11440638 | 0.83 | CYP2C9 (0.44) | ALDH1A1HSD17B10CASP6CTDSP1PLG | |
| SCHEMBL11424933 | 0.82 | ALDH1A1 (0.42) | ALDH1A1HSD17B10CASP6CTDSP1CA12 | |
| SCHEMBL11421980 | 0.82 | KCNMA1 (0.51) | ALDH1A1KCNMA1POLBCYP1A2GAA | |
| SCHEMBL11440870 | 0.81 | RAB9A (0.47) | ALDH1A1HSD17B10KCNMA1PLGKLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216165-A | Amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |