Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | PLK1 | P53350 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | NQO1 | P15559 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SCN1A | P35498 | 1/20 | 0.50 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.50 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21636224 | 0.91 | L3MBTL1 (0.54) | PARP10PLK1ALDH1A1GAAKMT2A | |
| SCHEMBL21636259 | 0.89 | L3MBTL1 (0.53) | NPC1GAAPLA2G4BKMT2AL3MBTL1 | |
| SCHEMBL12732996 | 0.88 | L3MBTL1 (0.57) | PLK1ALDH1A1PLA2G4BKMT2ANPSR1 | |
| SCHEMBL1367365 | 0.86 | PARP10 (0.70) | PARP10NPC1PLK1ALDH1A1PLA2G4B | |
| SCHEMBL906436 | 0.85 | CES2 (0.64) | PARP10ALDH1A1MAPT | |
| SCHEMBL7531547 | 0.85 | L3MBTL1 (0.46) | PARP10PLK1ALDH1A1GAAKMT2A | |
| SCHEMBL21636280 | 0.85 | L3MBTL1 (0.49) | PARP10ALDH1A1GAAKMT2AL3MBTL1 | |
| SCHEMBL10374298 | 0.85 | MAPT (0.51) | PARP10NPC1PLK1GAARAB9A | |
| SCHEMBL21636222 | 0.84 | TP53 (0.65) | GAAPLA2G4B | |
| SCHEMBL9402688 | 0.84 | TP53 (0.65) | GAAPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104105485-A | Acc inhibitors and uses thereof | NIMBUS APOLLO INC | 2014-10-15 | — | — | CN | disclosed |
| US-4239779-A | AND AS A HYPOGLYCEMIC AGENT | PFIZER INC. (US) | 1980-12-16 | — | — | US | disclosed |
| US-4219566-A | TREATMENT OF ISCHEMIC HEART DISEASE AND HYPERGLYCEMIA OF DIABETES | PFIZER INC. (US) | 1980-08-26 | — | — | US | disclosed |