Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | ULK1 | O75385 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11426294 | 0.88 | CASP6 (0.51) | HSD17B10SMN1; SMN2NPSR1HDAC1MAPT | |
| SCHEMBL11761572 | 0.87 | HSD17B10 (0.51) | HSD17B10SMN1; SMN2NPSR1HDAC1MAPT | |
| SCHEMBL11440869 | 0.85 | HPSE (0.42) | HSD17B10HDAC1MAPTMEN1KMT2A | |
| SCHEMBL10909111 | 0.85 | KMT2A (0.47) | HSD17B10SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL11339146 | 0.85 | RECQL (0.54) | HSD17B10SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL11829001 | 0.84 | SMN1; SMN2 (0.53) | HSD17B10SMN1; SMN2NPSR1HDAC1MAPT | |
| SCHEMBL11431004 | 0.84 | HDAC1 (0.53) | HSD17B10SMN1; SMN2NPSR1HDAC1MAPT | |
| SCHEMBL11426177 | 0.84 | HPSE (0.42) | HSD17B10HDAC1MAPTMEN1KMT2A | |
| SCHEMBL11436291 | 0.82 | HSD17B10 (0.51) | HSD17B10SMN1; SMN2NPSR1HDAC1MAPT | |
| SCHEMBL11442222 | 0.82 | RAB9A (0.59) | SMN1; SMN2MAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216165-A | Amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |