Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.68 |
| ▸ | CMA1 | P23946 | 1/20 | 0.56 |
| ▸ | GSK3A | P49840 | 2/20 | 0.53 |
| ▸ | GSK3B | P49841 | 2/20 | 0.53 |
| ▸ | ACACB | O00763 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4509396 | 0.90 | ACACB (0.64) | GAACMA1GSK3AGSK3BACACB | |
| SCHEMBL3459387 | 0.90 | L3MBTL1 (0.64) | GAACMA1GSK3AGSK3BACACB | |
| SCHEMBL20303832 | 0.89 | L3MBTL1 (0.67) | GAACMA1GSK3AGSK3BACACB | |
| SCHEMBL2874555 | 0.87 | GAA (0.61) | GAACMA1GSK3AGSK3BACACB | |
| SCHEMBL15723517 | 0.85 | SMN1; SMN2 (0.61) | GAACMA1ACACBMEN1ALDH1A1 | |
| SCHEMBL22367284 | 0.84 | GAA (0.51) | GAAALDH1A1MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL11432099 | 0.83 | SIGMAR1 (0.60) | GAAGSK3AGSK3BSIGMAR1MEN1 | |
| SCHEMBL17360667 | 0.82 | CMA1 (0.59) | GAACMA1GSK3AGSK3BSIGMAR1 | |
| SCHEMBL158547 | 0.82 | GAA (0.55) | GAACMA1GSK3AGSK3BACACB | |
| SCHEMBL29607421 | 0.81 | GAA (1.00) | GAACMA1GSK3AGSK3BSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0023097-A1 | De-arylmethylation of N-mono- or N-diarylmethyl-beta-lactams; novel azetizinones having anti-bacterial activity | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-01-28 | — | — | EP | disclosed |