Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 4/20 | 0.50 |
| ▸ | CASP6 | P55212 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | NSD2 | O96028 | 2/20 | 0.44 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.44 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 2/20 | 0.40 |
| ▸ | TIMP3 | P35625 | 3/20 | 0.39 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.37 |
| ▸ | RECQL | P46063 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11432315 | 0.99 | NT5E (0.51) | NT5ECASP6ALDH1A1HSD17B10CYP2C9 | |
| SCHEMBL11432534 | 0.93 | CASP6 (0.50) | NT5ECASP6ALDH1A1HSD17B10CYP2C9 | |
| SCHEMBL11432539 | 0.92 | CASP6 (0.51) | NT5ECASP6ALDH1A1HSD17B10CYP2C9 | |
| SCHEMBL11565609 | 0.85 | APEX1 (0.59) | NT5ECASP6ALDH1A1HSD17B10CYP2C9 | |
| SCHEMBL11426244 | 0.85 | APEX1 (0.46) | NT5ECASP6ALDH1A1HSD17B10CYP2C9 | |
| SCHEMBL11438960 | 0.84 | PRMT1 (0.53) | NT5ECASP6ALDH1A1HSD17B10CYP2C9 | |
| SCHEMBL11565618 | 0.84 | APEX1 (0.60) | NT5ECASP6ALDH1A1HSD17B10CYP2C9 | |
| SCHEMBL11437999 | 0.84 | RAPGEF4 (0.41) | NT5ECASP6ALDH1A1HSD17B10CYP2C9 | |
| SCHEMBL11151522 | 0.83 | APEX1 (0.47) | NT5ECASP6ALDH1A1HSD17B10CYP2C9 | |
| SCHEMBL11426261 | 0.83 | APEX1 (0.47) | NT5ECASP6ALDH1A1HSD17B10CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4229584-A | Ureylenebis(anionic substituted phenylene carbonyl)imino naphthalene sulfonic acids and naphthalene carboxylic acids and their salts | AMERICAN CYANAMID COMPANY (US) | 1980-10-21 | — | — | US | disclosed |
| US-4177209-A | COMPLEMENT INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1979-12-04 | — | — | US | disclosed |
| US-4129590-A | INHIBITORS OF THE COMPLEMENT SYSTEM | AMERICAN CYANAMID COMPANY (US) | 1978-12-12 | — | — | US | disclosed |