SCHEMBL11434366

SCHEMBL11434366

ClCCOP(OCCCl)Oc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.48
TP53 P04637 1/20 0.48
KCNA3 P22001 1/20 0.38
TAAR1 Q96RJ0 1/20 0.34
RECQL P46063 1/20 0.34
LTA4H P09960 3/20 0.33
TSHR P16473 1/20 0.33
HTR1B P28222 2/20 0.31
HDAC3 O15379 1/20 0.31
HDAC4 P56524 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC7 Q8WUI4 1/20 0.31
HDAC2 Q92769 1/20 0.31
HDAC10 Q969S8 1/20 0.31
HDAC11 Q96DB2 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
HDAC9 Q9UKV0 1/20 0.31
HDAC5 Q9UQL6 1/20 0.31
DRD2 P14416 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5599905 0.96 ALDH1A1 (0.48) ALDH1A1TP53KCNA3TAAR1RECQL
SCHEMBL14354354 0.82 KCNA3 (0.44) ALDH1A1KCNA3TAAR1RECQLLTA4H
SCHEMBL1727346 0.79 LTA4H (0.42) ALDH1A1KCNA3TAAR1RECQLLTA4H
SCHEMBL11064974 0.79 KCNA3 (0.34) ALDH1A1TP53KCNA3TAAR1RECQL
SCHEMBL25813074 0.78 KCNA3 (0.46) ALDH1A1KCNA3TAAR1RECQLLTA4H
SCHEMBL445915 0.76 LTA4H (0.53) ALDH1A1KCNA3RECQLLTA4HTSHR
SCHEMBL1724774 0.75 LTA4H (0.42) ALDH1A1KCNA3TAAR1RECQLLTA4H
SCHEMBL685508 0.75 ALDH1A1 (0.54) ALDH1A1KCNA3TAAR1RECQLLTA4H
SCHEMBL21920140 0.75 KDM4E (0.35) ALDH1A1KCNA3TAAR1RECQLLTA4H
SCHEMBL991869 0.75 LTA4H (0.53) ALDH1A1TP53KCNA3LTA4HTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4202844-A OXIDATION OF ORGANIC PHOSPHITES WITH NITROGEN DIOXIDE AS CATALYST TENNECO CHEMICALS, INC. (US) 1980-05-13 US disclosed