SCHEMBL11064974

SCHEMBL11064974

ClCCOP(CCCl)Oc1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KCNA3 P22001 1/20 0.34
ALDH1A1 P00352 2/20 0.33
TP53 P04637 1/20 0.33
TAAR1 Q96RJ0 1/20 0.31
RECQL P46063 1/20 0.31
LTA4H P09960 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11065817 0.82 CYP3A4 (0.33) ALDH1A1TP53TSHR
SCHEMBL5599905 0.79 ALDH1A1 (0.48) KCNA3ALDH1A1TP53TAAR1RECQL
SCHEMBL11434366 0.79 ALDH1A1 (0.48) KCNA3ALDH1A1TP53TAAR1RECQL
SCHEMBL11069320 0.76 TSHR (0.39) ALDH1A1TP53TSHR
SCHEMBL6902615 0.74 LTA4H (0.39) KCNA3LTA4H
SCHEMBL1726956 0.72 ALDH1A1 (0.53) ALDH1A1TP53
SCHEMBL10631751 0.71 ALDH1A1 (0.37) ALDH1A1TP53RECQLTSHR
SCHEMBL11153749 0.70 LTA4H (0.49) KCNA3ALDH1A1TP53LTA4HTSHR
SCHEMBL9064616 0.70 LTA4H (0.49) KCNA3ALDH1A1TP53LTA4HTSHR
SCHEMBL11074250 0.69 KCNA3 (0.44) KCNA3ALDH1A1TAAR1RECQLLTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4446061-A FIREPROOFING, SMOKELESS, PHOSPHITE/PHOSPHONATE MONSANTO COMPANY (US) 1984-05-01 US disclosed
US-4260542-A FLAME RETARDANTS, SMOKE SUPPRESSANTS MONSANTO COMPANY (US) 1981-04-07 US disclosed
US-4206133-A FLAME RETARDANTS AND SMOKE SUPPRESSANTS MONSANTO COMPANY (US) 1980-06-03 US disclosed
US-4133823-A FIREPROOFING, SMOKELESS MONSANTO COMPANY (US) 1979-01-09 US disclosed