SCHEMBL1143451

SCHEMBL1143451

CCN(CC)S(=O)(=O)c1ccc(OC)c(N)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.72
SMN1; SMN2 Q16637 1/20 0.68
ALDH1A1 P00352 3/20 0.66
MAPT P10636 1/20 0.66
MEN1 O00255 1/20 0.60
KMT2A Q03164 1/20 0.60
KDM4E B2RXH2 2/20 0.55
CA1 P00915 1/20 0.55
CA2 P00918 1/20 0.55
MMP1 P03956 1/20 0.55
MMP2 P08253 1/20 0.55
MMP9 P14780 1/20 0.55
MMP8 P22894 1/20 0.55
MMP13 P45452 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.54
TSHR P16473 1/20 0.52
F2 P00734 1/20 0.52
PRSS1 P07477 1/20 0.52
PRSS2 P07478 1/20 0.52
PRSS3 P35030 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30414489 1.00 POLB (0.72) POLBSMN1; SMN2ALDH1A1MAPTMEN1
SCHEMBL9400292 0.88 ALDH1A1 (0.70) POLBSMN1; SMN2ALDH1A1MAPTMEN1
SCHEMBL11311669 0.86 LMNA (0.59) POLBSMN1; SMN2ALDH1A1MAPTMEN1
SCHEMBL9862155 0.86 SMN1; SMN2 (0.63) POLBSMN1; SMN2ALDH1A1MAPTMEN1
SCHEMBL11110731 0.85 L3MBTL1 (0.56) POLBSMN1; SMN2ALDH1A1MAPTMEN1
SCHEMBL7204676 0.85 ALDH1A1 (0.77) POLBSMN1; SMN2ALDH1A1MAPTKDM4E
SCHEMBL13997417 0.83 ALDH1A1 (0.68) POLBSMN1; SMN2ALDH1A1MAPTMEN1
SCHEMBL6123467 0.82 MAPT (0.61) POLBSMN1; SMN2ALDH1A1MAPTMEN1
SCHEMBL939122 0.82 POLB (0.63) POLBSMN1; SMN2ALDH1A1MAPTMEN1
SCHEMBL11179508 0.81 ALDH1A1 (0.66) POLBSMN1; SMN2ALDH1A1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 213 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116119833-B Nutrient for water recovery system and preparation method and application thereof 嘉兴沃特泰科环保科技股份有限公司 2023-09-08 CN claimed
CN-115403959-B Preparation method of polarity-difference multicolor resin coating stock solution 扬州市祥华新材料科技有限公司 2023-08-18 CN claimed
CN-116119833-A Nutrient for water recovery system and preparation method and application thereof 嘉兴沃特泰科环保科技股份有限公司 2023-05-16 CN claimed
CN-115403959-A Preparation method of colorful resin coating stock solution with polarity difference 扬州市祥华新材料科技有限公司 2022-11-29 CN claimed
US-9353051-B2 Antiviral drugs for treatment or prevention of dengue infection SIGA TECHNOLOGIES, INC. (US) 2016-05-31 US claimed
CN-103159904-B High-molecular polymer dye or pigment with adjustable color and preparation method thereof SHANGHAI SUNVEA CHEMICAL INDUSTRY MATERIAL CO LTD 2015-05-20 CN claimed
US-20130303491-A1 Antiviral Drugs for Treatement or Prevention of Dengue Infection SIGA TECHNOLOGIES INC. (US) 2013-11-14 US claimed
US-8518960-B2 Antiviral drugs for treatment or prevention of dengue infection SIGA TECHNOLOGIES, INC. (US) 2013-08-27 US claimed
CN-103159904-A High-molecular polymer dye or pigment with adjustable color and preparation method thereof SHANGHAI XUANYANG CHEMICAL MATERIAL SCIENCE & TECHNOLOGY CO LTD 2013-06-19 CN claimed
US-20100189685-A1 Antiviral Drugs for Treatment or Prevention of Dengue Infection SIGA TECHNOLOGIES, INC. 2010-07-29 US claimed
US-5766841-A USING ENZYME OKLAHOMA MEDICAL RESEARCH FOUNDATION (US) 1998-06-16 US claimed
EP-0566633-A4 METHOD FOR VISUALLY DETECTING THE PRESENCE OF A VIRUS IN A CLINICAL SPECIMEN. SYMEX CORP (US) 1994-12-14 EP claimed
EP-0566633-A1 METHOD FOR VISUALLY DETECTING THE PRESENCE OF A VIRUS IN A CLINICAL SPECIMEN SYMEX CORP. (US) 1993-10-27 EP claimed
US-5252458-A Concentrating precipitating chromogen SYMEX CORP. (US) 1993-10-12 US claimed
WO-1993019143-A1 COLORANT-CONTAINING ELECTRORHEOLOGICAL MATERIALS LORD CORPORATION (US) 1993-09-30 WO claimed
WO-1992012256-A1 METHOD FOR VISUALLY DETECTING THE PRESENCE OF A VIRUS IN A CLINICAL SPECIMEN SYMEX CORP. (US) 1992-07-23 WO claimed
US-4965237-A AROMATICITY-POSESSING ISOCYANATE COMPOUND, IMINO COMPOUND, AND ANILINE DERIVATIVE MITSUBISHI PAPER MILLS, LTD. (JP) 1990-10-23 US claimed
US-4510239-A Double antibody immunoassays of enzymes such as prostatic acid phosphatase BECKMAN INSTRUMENTS, INC. (US) 1985-04-09 US claimed
US-4288362-A Monoazo pigments containing a quinazo linonylacetoacetanilide coupling component BAYER AKTIENGESELLSCHAFT (DE) 1981-09-08 US claimed
US-3941768-A One step diazotization coupling process CIBA-GEIGY AG (CH) 1976-03-02 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130303491-A1 Antiviral Drugs for Treatement or Prevention of Dengue Infection HAVCR2, EIF2AK2, ZC3HAV1 POLB 3351/4885SMN1; SMN2 767/4885ALDH1A1 2277/4885
US-20100189685-A1 Antiviral Drugs for Treatment or Prevention of Dengue Infection EIF2AK2, HAVCR2, SNRPE POLB 2930/4885SMN1; SMN2 509/4885ALDH1A1 2072/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.