Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CASP1 | P29466 | 2/20 | 0.49 |
| ▸ | CASP7 | P55210 | 2/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11075495 | 0.90 | TLR7 (0.50) | TLR7KDM4EMAPTCASP1CASP7 | |
| SCHEMBL11434898 | 0.84 | TLR7 (0.49) | TLR7KDM4EMAPTCASP1CASP7 | |
| SCHEMBL11449199 | 0.83 | TLR7 (0.46) | TLR7KDM4EMAPTCASP1CASP7 | |
| SCHEMBL9611690 | 0.83 | TLR7 (0.61) | TLR7KDM4EMAPTHSD11B1NPC1 | |
| SCHEMBL11082315 | 0.77 | TLR7 (0.55) | TLR7KDM4EHSD11B1CYP1A2ATM | |
| SCHEMBL11440934 | 0.75 | TLR7 (0.49) | TLR7MAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL11081129 | 0.75 | PARP1 (0.48) | KDM4EMAPTRAB9ACYP3A4ALDH1A1 | |
| SCHEMBL11084034 | 0.75 | TLR7 (0.46) | TLR7KDM4EHSD11B1CYP2C9ATM | |
| SCHEMBL11184964 | 0.75 | TLR7 (0.51) | TLR7KDM4EMAPTNPC1RAB9A | |
| SCHEMBL16692144 | 0.74 | TLR7 (0.48) | TLR7KDM4EMAPTHSD11B1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435417-A | ANTIINFLAMMATORY AGENTS | GRUPPO LEPETIT S.P.A. (IT) | 1984-03-06 | — | — | US | disclosed |
| EP-0012866-A1 | New 3H-naphtho(1,2-d)imidazoles, processes for preparing them, compounds for use as antiinflammatory and antimicrobial agents and compositions for that use containing them | GRUPPO LEPETIT S.P.A. (IT) | 1980-07-09 | — | — | EP | disclosed |