Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11440934 | 0.87 | TLR7 (0.49) | TLR7ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL11434898 | 0.85 | TLR7 (0.49) | TLR7KDM4ELMNAHTTADORA3 | |
| SCHEMBL9611690 | 0.84 | TLR7 (0.61) | TLR7KDM4ELMNAHTTADORA3 | |
| SCHEMBL11079289 | 0.83 | TLR7 (0.51) | TLR7KDM4ELMNAHTTADORA3 | |
| SCHEMBL11075495 | 0.82 | TLR7 (0.50) | TLR7KDM4ELMNAHTTADORA3 | |
| SCHEMBL11182201 | 0.82 | PSEN1 (0.45) | TLR7KDM4EHTTADORA2AMAPT | |
| SCHEMBL11443172 | 0.81 | TLR7 (0.45) | TLR7KDM4ELMNAHTTMAPT | |
| SCHEMBL16692216 | 0.79 | TLR7 (0.49) | TLR7KDM4ELMNAHTTMAPT | |
| SCHEMBL11184964 | 0.79 | TLR7 (0.51) | TLR7KDM4ELMNAHTTMAPT | |
| SCHEMBL11448832 | 0.78 | TLR7 (0.46) | TLR7KDM4ELMNAMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0012866-A1 | New 3H-naphtho(1,2-d)imidazoles, processes for preparing them, compounds for use as antiinflammatory and antimicrobial agents and compositions for that use containing them | GRUPPO LEPETIT S.P.A. (IT) | 1980-07-09 | — | — | EP | disclosed |