Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11434854 | 0.98 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2LMNAHSD17B10MEN1 | |
| SCHEMBL11429562 | 0.85 | ALDH1A1 (0.30) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11429197 | 0.83 | — | — | |
| SCHEMBL2863417 | 0.78 | EPHX1 (0.46) | ALDH1A1TSHR | |
| SCHEMBL117144 | 0.77 | LMNA (0.44) | ALDH1A1SMN1; SMN2LMNAHSD17B10MEN1 | |
| SCHEMBL11434794 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL11427358 | 0.74 | — | — | |
| SCHEMBL13477326 | 0.74 | CA1 (0.33) | — | |
| SCHEMBL31375083 | 0.73 | TSHR (0.36) | ALDH1A1TSHR | |
| SCHEMBL4175876 | 0.72 | TSHR (0.39) | ALDH1A1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4201725-A | TRISUBSTITUTED METHYL-N-METHYLAMINE, PARKINSON*S DISEASE, ANTISPASMODIC AGENTS | LABAZ (FR) | 1980-05-06 | — | — | US | disclosed |
| US-4057644-A | PARKINSON'S DISEASE | LABAZ (FR) | 1977-11-08 | — | — | US | disclosed |