Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | MAT2A | P31153 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11707876 | 0.88 | HSD11B1 (0.44) | KDM4EMAT2AMAPK1MAPTMEN1 | |
| SCHEMBL11707214 | 0.86 | KDM4E (0.48) | KDM4EMAPK1MAPTMEN1KMT2A | |
| SCHEMBL11710604 | 0.84 | KMT2A (0.46) | KDM4EMAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL11706191 | 0.84 | KDM4E (0.47) | KDM4EMAT2AMAPK1MAPTCASP1 | |
| SCHEMBL11707641 | 0.83 | POLB (0.56) | KDM4EMAPK1MAPTMEN1KMT2A | |
| SCHEMBL11706112 | 0.83 | PTAFR (0.59) | MAPTPOLBLMNASMN1; SMN2PTAFR | |
| SCHEMBL11706511 | 0.82 | CASR (0.52) | KDM4EMEN1KMT2AHSD17B10POLB | |
| SCHEMBL11706193 | 0.81 | LMNA (0.44) | KDM4EMAT2AMAPK1MAPTMEN1 | |
| SCHEMBL11707843 | 0.81 | DHODH (0.44) | KDM4EMEN1KMT2AHSD17B10POLB | |
| SCHEMBL11706300 | 0.80 | KMT2A (0.39) | KDM4EMAT2AMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4002755-A | Triazoloquinazolines | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-01-11 | — | — | US | claimed |
| US-4183932-A | Fused quinazolinones and preparation thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-01-15 | — | — | US | disclosed |
| US-4002755-A | Triazoloquinazolines | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-01-11 | — | — | US | disclosed |