Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAT2A | P31153 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11706977 | 0.87 | LMNA (0.44) | KDM4EMAPK1MAT2AMAPTTP53 | |
| SCHEMBL11435230 | 0.84 | KDM4E (0.46) | KDM4EMAPK1MAT2AMAPTTP53 | |
| SCHEMBL11707876 | 0.82 | HSD11B1 (0.44) | KDM4EMAPK1MAT2AMAPTTP53 | |
| SCHEMBL11706193 | 0.78 | LMNA (0.44) | KDM4EMAPK1MAT2AMAPTTP53 | |
| SCHEMBL11705682 | 0.77 | MAPT (0.39) | KDM4EMAPK1MAT2AMAPTTP53 | |
| SCHEMBL11708433 | 0.75 | PIK3CB (0.39) | KDM4EMAPK1MAT2AMAPTTP53 | |
| SCHEMBL11707868 | 0.74 | PIK3CB (0.38) | KDM4EMAPK1MAT2AMAPTTP53 | |
| SCHEMBL11437186 | 0.73 | FNTA (0.52) | KDM4EMAPK1MAT2AMAPTTP53 | |
| SCHEMBL11441866 | 0.72 | FNTA (0.52) | KDM4EMAPK1MAT2AMAPTTP53 | |
| SCHEMBL11157753 | 0.71 | MAPT (0.61) | KDM4EMAPK1MAPTTP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4002755-A | Triazoloquinazolines | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-01-11 | — | — | US | disclosed |