Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11496531 | 0.87 | GAA (0.38) | KDM4EGAADCUN1D1RAB9ASMN1; SMN2 | |
| SCHEMBL29202958 | 0.85 | GAA (0.37) | KDM4EGAADCUN1D1RAB9ASMN1; SMN2 | |
| SCHEMBL29202957 | 0.84 | GAA (0.36) | KDM4EGAADCUN1D1HPGDALDH1A1 | |
| SCHEMBL29202956 | 0.84 | GAA (0.36) | KDM4EGAADCUN1D1HPGDALDH1A1 | |
| Alcohol SCHEMBL9348509 | 0.79 | DPP4 (0.39) | KDM4EGAADCUN1D1RAB9ASMN1; SMN2 | |
| SCHEMBL284418 | 0.79 | HTR7 (0.44) | GAADCUN1D1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL8583338 | 0.78 | DPP4 (0.42) | KDM4EGAADCUN1D1RAB9ASMN1; SMN2 | |
| SCHEMBL284040 | 0.77 | GAA (0.36) | POLBGAADCUN1D1RAB9ASMN1; SMN2 | |
| SCHEMBL8514983 | 0.77 | DRD2 (0.36) | GAATSHRNPSR1MEN1LMNA | |
| SCHEMBL5434984 | 0.77 | SIGMAR1 (0.39) | KDM4EGAADCUN1D1SMN1; SMN2HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4212754-A | LIGANDS CONTAINING AMINE, HYDROXY, OXAZOLINE, AND IMIDAZOLINE GROUPS | MOBIL OIL CORPORATION (US) | 1980-07-15 | — | — | US | claimed |