Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 5/20 | 0.47 |
| ▸ | KLK1 | P06870 | 5/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 7/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 2/20 | 0.41 |
| ▸ | NT5E | P21589 | 1/20 | 0.40 |
| ▸ | FADS1 | O60427 | 1/20 | 0.40 |
| ▸ | KLK6 | Q92876 | 4/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | PLAT | P00750 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11427837 | 0.91 | PLG (0.49) | PLGKLK1ENPP2CASP6CTDSP1 | |
| SCHEMBL11428140 | 0.85 | PLAU (0.46) | PLGKLK1CASP6CTDSP1PLAU | |
| SCHEMBL11438365 | 0.85 | TNF (0.45) | PLGKLK1ENPP2MEN1KMT2A | |
| SCHEMBL11440412 | 0.84 | ENPP2 (0.43) | PLGKLK1ENPP2CASP6CTDSP1 | |
| SCHEMBL11427501 | 0.84 | NPC1 (0.45) | PLGKLK1ENPP2CASP6CTDSP1 | |
| SCHEMBL11204762 | 0.83 | NT5E (0.62) | PLGKLK1ENPP2CASP6CTDSP1 | |
| SCHEMBL11433703 | 0.83 | TNF (0.48) | PLGKLK1ENPP2MEN1KMT2A | |
| SCHEMBL11433818 | 0.82 | PTGES (0.41) | PLGKLK1ENPP2PLAUNT5E | |
| SCHEMBL11435442 | 0.82 | CASP6 (0.49) | ENPP2CASP6CTDSP1NT5EMEN1 | |
| SCHEMBL11440916 | 0.82 | CASP6 (0.64) | PLGKLK1ENPP2CASP6CTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216165-A | Amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |