SCHEMBL11435665

SCHEMBL11435665

CCNP(=O)(OCC)C(Cl)(Cl)C(=O)OC(C)(C)C

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
DGAT1 O75907 1/20 0.34
GAA P10253 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.31
TP53 P04637 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA9 Q16790 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11435662 0.80 GAA (0.38) CYP3A4CYP2C9CYP2C19GAASMN1; SMN2
SCHEMBL8099688 0.78 CYP3A4 (0.36) CYP3A4CYP2C9CYP2C19DGAT1GAA
SCHEMBL11442582 0.72 CYP3A4 (0.32) CYP3A4CYP2C9CYP2C19DGAT1GAA
SCHEMBL10308649 0.72 TSHR (0.40) CYP2C9CYP2C19GAATP53TDP1
SCHEMBL11431291 0.69 DGAT1 (0.33) DGAT1
SCHEMBL1240221 0.68 CYP3A4 (0.33) CYP3A4CYP2C9CYP2C19DGAT1GAA
SCHEMBL11430898 0.66 DGAT1 (0.37) DGAT1
SCHEMBL7473418 0.65 DGAT1 (0.35) DGAT1TP53TDP1CA12CA1
SCHEMBL14819108 0.64 CA1 (0.39) CYP3A4CYP2C9CYP2C19GAATDP1
SCHEMBL7674935 0.64 DGAT1 (0.43) DGAT1GAACA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4228109-A HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-10-14 US claimed