Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1201418 | 0.83 | DGAT1 (0.48) | DGAT1 | |
| SCHEMBL5877421 | 0.77 | DGAT1 (0.35) | DGAT1KDM4E | |
| SCHEMBL2923540 | 0.73 | DGAT1 (0.38) | DGAT1GAAHTTCA12CA1 | |
| SCHEMBL8099688 | 0.73 | CYP3A4 (0.36) | DGAT1GAACA12CA1CA2 | |
| SCHEMBL7473418 | 0.73 | DGAT1 (0.35) | DGAT1CA12CA1CA2CA9 | |
| SCHEMBL5554985 | 0.72 | PTPN1 (0.46) | ALDH1A1GAA | |
| SCHEMBL6120239 | 0.70 | L3MBTL1 (0.34) | DGAT1 | |
| SCHEMBL11143316 | 0.69 | PPARD (0.34) | DGAT1GAACA12CA1CA2 | |
| SCHEMBL2461103 | 0.69 | DGAT1 (0.39) | DGAT1 | |
| SCHEMBL1240221 | 0.69 | CYP3A4 (0.33) | DGAT1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020115692-A1 | Tryptophan derivatives | CELLTECH R&D, LTD. (GB) | 2002-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020115692-A1 | Tryptophan derivatives | IDO1, TPH1, IDO2 | DGAT1 3672/4885KDM4E 3104/4885ALDH1A1 103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.