Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | PTPRF | P10586 | 1/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11438337 | 0.88 | ALDH1A1 (0.43) | ALDH1A1KMT2ACHRM2CHRM3GLA | |
| SCHEMBL11437571 | 0.83 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2ACHRM2CHRM3 | |
| SCHEMBL11436721 | 0.80 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2ACHRM2CHRM3 | |
| SCHEMBL11450497 | 0.79 | MAPK1 (0.40) | ALDH1A1MEN1KMT2ACHRM2CHRM3 | |
| SCHEMBL11339656 | 0.78 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2ACHRM2CHRM3 | |
| SCHEMBL11435695 | 0.76 | CHRM3 (0.39) | ALDH1A1MEN1KMT2ACHRM2CHRM3 | |
| SCHEMBL11446841 | 0.75 | SIGMAR1 (0.40) | ALDH1A1MEN1KMT2ACHRM2CHRM3 | |
| SCHEMBL11434770 | 0.75 | MEN1 (0.39) | ALDH1A1MEN1KMT2ACHRM2CHRM3 | |
| SCHEMBL11442174 | 0.74 | MEN1 (0.45) | ALDH1A1MEN1KMT2ACHRM2CHRM3 | |
| SCHEMBL11454719 | 0.74 | MEN1 (0.38) | ALDH1A1MEN1KMT2ACHRM2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4217362-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1980-08-12 | — | — | US | disclosed |
| US-4212888-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1980-07-15 | — | — | US | disclosed |
| US-4128663-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1978-12-05 | — | — | US | disclosed |