Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11450504 | 0.90 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL11450497 | 0.89 | MAPK1 (0.40) | ALDH1A1SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL11438327 | 0.89 | MEN1 (0.39) | ALDH1A1SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL11437571 | 0.88 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL11446841 | 0.85 | SIGMAR1 (0.40) | ALDH1A1SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL11339656 | 0.83 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL11437911 | 0.82 | RAB9A (0.37) | ALDH1A1KMT2ANPC1RAB9ASIGMAR1 | |
| SCHEMBL11446987 | 0.82 | CNR2 (0.39) | ALDH1A1SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL11434770 | 0.82 | MEN1 (0.39) | ALDH1A1SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL11332175 | 0.81 | SIGMAR1 (0.42) | ALDH1A1SMN1; SMN2MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4128663-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1978-12-05 | — | — | US | claimed |
| US-4217362-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1980-08-12 | — | — | US | disclosed |
| US-4212888-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1980-07-15 | — | — | US | disclosed |
| US-4128663-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1978-12-05 | — | — | US | disclosed |