Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.34 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11434967 | 0.76 | BACE1 (0.37) | HSP90AA1HSP90AB1MAPTALDH1A1LMNA | |
| SCHEMBL855885 | 0.75 | HTT (0.43) | DYRK1ADYRK1BMAPTKMT2ANPC1 | |
| SCHEMBL11429685 | 0.74 | MEN1 (0.38) | MAPTKMT2AALDH1A1MEN1LMNA | |
| SCHEMBL9682919 | 0.70 | EGFR (0.43) | KMT2AALDH1A1SMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL11435307 | 0.69 | MAPK1 (0.46) | MAPTKMT2AALDH1A1MEN1LMNA | |
| SCHEMBL25355933 | 0.68 | ALOX15 (0.62) | MAPTKMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL29969018 | 0.67 | HRH3 (0.39) | DYRK1ADYRK1BMAPTKMT2AALDH1A1 | |
| SCHEMBL21513740 | 0.67 | HRH3 (0.39) | DYRK1ADYRK1BMAPTKMT2AALDH1A1 | |
| SCHEMBL926427 | 0.65 | APP (0.52) | MAPTKMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL21513743 | 0.65 | KMT2A (0.34) | MAPTKMT2AALDH1A1MEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0013145-A2 | Substituted anilinopyridines, processes for their preparation and intermediates for use therein, compositions and herbicidal use thereof | ICI AUSTRALIA LIMITED (AU) | 1980-07-09 | — | — | EP | disclosed |