Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CD38 | P28907 | 5/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.39 |
| ▸ | MTOR | P42345 | 3/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11435882 | 0.82 | PARP1 (0.51) | ALDH1A1KMT2AMEN1MAPTRAB9A | |
| SCHEMBL12892209 | 0.77 | MAPT (0.52) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL2662445 | 0.77 | ALPL (0.61) | ALDH1A1SMN1; SMN2L3MBTL1KMT2AMAPT | |
| SCHEMBL11559491 | 0.76 | KDR (0.51) | ALDH1A1SMN1; SMN2L3MBTL1KMT2AMAPT | |
| SCHEMBL9501879 | 0.75 | NPC1 (0.56) | ALDH1A1SMN1; SMN2L3MBTL1KMT2AMEN1 | |
| SCHEMBL10880639 | 0.75 | ALPL (0.46) | ALDH1A1SMN1; SMN2L3MBTL1KMT2AMAPT | |
| SCHEMBL11195781 | 0.74 | MAPT (0.55) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL11442680 | 0.74 | MEN1 (0.43) | SMN1; SMN2KMT2AMEN1MAPTRAB9A | |
| SCHEMBL11428491 | 0.72 | KDM4E (0.56) | ALDH1A1SMN1; SMN2L3MBTL1KMT2AMEN1 | |
| SCHEMBL8612811 | 0.72 | GRM5 (0.57) | SMN1; SMN2MAPTRAB9AKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4186201-A | ANTIALLERGIC AGENTS | RIKER LABORATORIES, INC. (US) | 1980-01-29 | — | — | US | disclosed |
| US-4147694-A | ANTIALLERGENS, ANTIHISTAMINES | RIKER LABORATORIES, INC. (US) | 1979-04-03 | — | — | US | disclosed |