Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.51 |
| ▸ | PLAU | P00749 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | PLAT | P00750 | 1/20 | 0.47 |
| ▸ | KLK1 | P06870 | 1/20 | 0.47 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.47 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2662445 | 0.87 | ALPL (0.61) | ALPLALDH1A1KDM4EHPGDHTT | |
| SCHEMBL11557699 | 0.86 | TERT (0.40) | KDRPLAUF2F10PLG | |
| SCHEMBL10880639 | 0.85 | ALPL (0.46) | KDRALPLALDH1A1KDM4EHSD17B10 | |
| SCHEMBL11556569 | 0.84 | KDM4E (0.40) | ALPLALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL11560143 | 0.84 | MAPT (0.40) | KDRP2RX1ALPLKDM4ESMN1; SMN2 | |
| SCHEMBL11560867 | 0.83 | KLKB1 (0.50) | KDRPLAUF2F10PLAT | |
| SCHEMBL11559144 | 0.83 | HSPD1 (0.40) | F2ALPLALDH1A1KDM4EHSD17B10 | |
| SCHEMBL11562452 | 0.83 | ALDH1A1 (0.38) | KDRPLAUF2F10PLG | |
| SCHEMBL12310841 | 0.83 | MMP2 (0.45) | KDRALPLALDH1A1KDM4EHSD17B10 | |
| SCHEMBL11562864 | 0.83 | KLKB1 (0.53) | KLK1KLK5KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146631-A | ANTIALLERGENS, RESPIRATORY DISORDERS | MAY & BAKER LIMITED (GB) | 1979-03-27 | — | — | US | disclosed |