Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CD38 | P28907 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9501879 | 0.83 | NPC1 (0.56) | PARP1MAPTNPC1CASP3RAB9A | |
| SCHEMBL11436038 | 0.82 | ALDH1A1 (0.44) | MAPTGAACD38NPC1CASP3 | |
| SCHEMBL12892209 | 0.78 | MAPT (0.52) | MAPTGAANPC1RAB9AALDH1A1 | |
| SCHEMBL8612811 | 0.78 | GRM5 (0.57) | MAPTTP53NPC1RAB9AKDM4E | |
| SCHEMBL2662445 | 0.77 | ALPL (0.61) | MAPTTP53NPC1RAB9AALDH1A1 | |
| SCHEMBL11195781 | 0.77 | MAPT (0.55) | MAPTGAATP53NPC1RAB9A | |
| SCHEMBL10935200 | 0.76 | GRM5 (0.56) | MAPTTP53NPC1RAB9AKDM4E | |
| SCHEMBL10935209 | 0.76 | GRM5 (0.56) | MAPTTP53NPC1RAB9AKDM4E | |
| SCHEMBL11559491 | 0.76 | KDR (0.51) | MAPTGAATP53NPC1RAB9A | |
| SCHEMBL19206635 | 0.76 | MAPT (0.61) | PARP1MAPTGAACD38TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4186201-A | ANTIALLERGIC AGENTS | RIKER LABORATORIES, INC. (US) | 1980-01-29 | — | — | US | disclosed |
| US-4147694-A | ANTIALLERGENS, ANTIHISTAMINES | RIKER LABORATORIES, INC. (US) | 1979-04-03 | — | — | US | disclosed |