Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | NPC1 | O15118 | 6/20 | 0.42 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.38 |
| ▸ | CDK2 | P24941 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.38 |
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10955560 | 0.85 | MAPT (0.44) | ADORA2AALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL10955595 | 0.78 | MAPT (0.48) | ALDH1A1NPC1RAB9AMAPTPOLB | |
| SCHEMBL23929760 | 0.72 | RAB9A (0.53) | ADORA2AALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL10952598 | 0.72 | MAPT (0.63) | ALDH1A1NPC1RAB9AMAPTMEN1 | |
| SCHEMBL6761935 | 0.72 | ALDH1A1 (0.55) | ADORA2AALDH1A1NPC1RAB9APOLB | |
| Bromide SCHEMBL6123463 | 0.71 | SMN1; SMN2 (0.44) | ALDH1A1NPC1RAB9AMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL6113899 | 0.71 | RXFP1 (0.44) | ALDH1A1NPC1RAB9AMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL8552956 | 0.71 | ALDH1A1 (0.53) | ADORA2AALDH1A1NPC1RAB9APOLB | |
| SCHEMBL3067153 | 0.71 | ALDH1A1 (0.40) | ADORA2AALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL10955467 | 0.70 | CLK2 (0.65) | ALDH1A1NPC1RAB9AMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0008047-A1 | 5(6)-(2-Amino-5-thiazoloyl)benzimidazole-2-carbamic acid esters and their salts, their preparation and use, and pharmaceutical compositions containing them | CIBA-GEIGY AG (CH) | 1980-02-20 | — | — | EP | disclosed |