Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10979420 | 0.82 | SMN1; SMN2 (0.40) | ALDH1A1LMNAHPGDSMN1; SMN2CYP2C19 | |
| SCHEMBL10985417 | 0.81 | CYP2C19 (0.43) | ALDH1A1LMNASMN1; SMN2CYP2C19MTOR | |
| SCHEMBL4445401 | 0.77 | MTOR (0.52) | ALDH1A1LMNAMAPTHTTSMN1; SMN2 | |
| SCHEMBL4841608 | 0.75 | TAAR1 (0.40) | ALDH1A1LMNAMAPTHTTSMN1; SMN2 | |
| SCHEMBL10989196 | 0.75 | RAB9A (0.41) | ALDH1A1LMNAHTTSMN1; SMN2CYP2C19 | |
| SCHEMBL3297741 | 0.74 | SMN1; SMN2 (0.43) | ALDH1A1LMNAMAPTHTTHPGD | |
| SCHEMBL3293876 | 0.73 | SMN1; SMN2 (0.59) | ALDH1A1LMNAHTTSMN1; SMN2TSHR | |
| SCHEMBL4843164 | 0.73 | SMN1; SMN2 (0.59) | ALDH1A1LMNAHTTSMN1; SMN2TSHR | |
| SCHEMBL11830020 | 0.72 | APAF1 (0.44) | ALDH1A1LMNAMAPTHTTHPGD | |
| Hydrochloric Acid SCHEMBL10586766 | 0.71 | HTT (0.38) | ALDH1A1HTTHPGDSMN1; SMN2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0008884-A1 | Derivatives of clavulanic acid, a process for their preparation and their compositions | BEECHAM GROUP PLC (GB) | 1980-03-19 | — | — | EP | disclosed |