Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10989196 | 0.88 | RAB9A (0.41) | MTORRAB9AGRM7CYP3A4ALOX15 | |
| SCHEMBL8458015 | 0.88 | MTOR (0.41) | MTORRAB9AGRM7CYP3A4ALOX15 | |
| Hydrochloric Acid SCHEMBL9769539 | 0.87 | CYP3A4 (0.42) | MTORRAB9AGRM7CYP3A4ALOX15 | |
| SCHEMBL10537184 | 0.86 | MTOR (0.40) | MTORRAB9AGRM7CYP3A4ALOX15 | |
| Hydrochloric Acid SCHEMBL7126952 | 0.85 | ALOX15 (0.42) | MTORRAB9AGRM7CYP3A4ALOX15 | |
| Hydrochloric Acid SCHEMBL8952425 | 0.84 | ALDH1A1 (0.50) | MTORRAB9AGRM7CYP3A4ALOX15 | |
| SCHEMBL4842155 | 0.84 | HPGD (0.45) | MTORRAB9AGRM7CYP3A4ALOX15 | |
| SCHEMBL10981498 | 0.84 | CYP2C19 (0.41) | MTORRAB9AGRM7CYP3A4ALOX15 | |
| SCHEMBL10979420 | 0.83 | SMN1; SMN2 (0.40) | MTORRAB9AGRM7CYP3A4ALOX15 | |
| SCHEMBL3297741 | 0.83 | SMN1; SMN2 (0.43) | MTORRAB9AGRM7CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090162314-A1 | Magnesium-Containing Polymers for the Treatment of Hyperphosphatemia | GENZYME CORPORATION | 2009-06-25 | — | — | US | disclosed |
| EP-1945196-A2 | MAGNESIUM-CONTAINING POLYMERS FOR HYPERPHOSPHATEMIA | Genzyme Corporation (US) | 2008-07-23 | — | — | EP | disclosed |
| WO-2007056405-A2 | MAGNESIUM-CONTAINING POLYMERS FOR THE TREATMENT OF HYPERPHOSPHATEMIA | GENZYME CORPORATION (US) | 2007-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090162314-A1 | Magnesium-Containing Polymers for the Treatment of Hyperphosphatemia | PPIP5K2, PHPT1, PHOSPHO1 | MTOR 992/4885RAB9A 3566/4885GRM7 639/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.