Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 7/20 | 0.55 |
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.53 |
| ▸ | SIRT1 | Q96EB6 | 4/20 | 0.53 |
| ▸ | MME | P08473 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5854507 | 0.85 | SLC1A3 (0.52) | FAAHSIRT2SIRT1CYP1A2SLC1A3 | |
| SCHEMBL5855554 | 0.85 | SLC1A3 (0.52) | FAAHSIRT2SIRT1CYP1A2SLC1A3 | |
| SCHEMBL5854503 | 0.85 | SLC1A3 (0.52) | FAAHSIRT2SIRT1CYP1A2SLC1A3 | |
| SCHEMBL8604298 | 0.84 | CYP1A2 (0.57) | FAAHSIRT2SIRT1MMECYP1A2 | |
| SCHEMBL5261067 | 0.84 | SLC1A3 (0.51) | SIRT2SIRT1SLC1A3 | |
| SCHEMBL5261062 | 0.84 | SLC1A3 (0.51) | SIRT2SIRT1SLC1A3 | |
| SCHEMBL3398263 | 0.83 | MGLL (0.62) | FAAH | |
| SCHEMBL21891962 | 0.83 | SIRT1 (0.61) | SIRT2SIRT1 | |
| SCHEMBL5259353 | 0.82 | NAALAD2 (0.56) | SLC1A3 | |
| SCHEMBL1834431 | 0.82 | NAALAD2 (0.56) | SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000023-B1 | OMEGA-SUBSTITUTED PENTYL UREAS, THEIR PREPARATION AND THEIR USE AS FUNGICIDES | BAYER AG (DE) | 1980-07-23 | — | — | EP | disclosed |
| US-4188401-A | Combating fungi with 1-(ω-substituted pentyl)-3-(2-cyano-acetyl)-ureas | BAYER AKTIENGESELLSCHAFT (DE) | 1980-02-12 | — | — | US | disclosed |
| EP-0000023-A1 | Omega-substituted pentyl ureas, their preparation and their use as fungicides | BAYER AG (DE) | 1978-12-20 | — | — | EP | disclosed |