Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 3/20 | 0.61 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11431631 | 0.94 | OPRK1 (0.65) | OPRK1PDE4DKMT2ANR1I2ADORA3 | |
| SCHEMBL11428583 | 0.86 | OPRK1 (0.53) | OPRK1PDE4DKMT2AMEN1 | |
| SCHEMBL11421538 | 0.86 | OPRK1 (0.50) | OPRK1PDE4DKMT2AMEN1HPGD | |
| SCHEMBL11432235 | 0.84 | MEN1 (0.49) | OPRK1PDE4DKMT2AMEN1HTT | |
| SCHEMBL11436107 | 0.84 | OPRK1 (0.45) | OPRK1PDE4DKMT2AMEN1HPGD | |
| SCHEMBL11425461 | 0.84 | MEN1 (0.51) | OPRK1PDE4DKMT2AMEN1HPGD | |
| SCHEMBL11425950 | 0.82 | L3MBTL1 (0.55) | OPRK1PDE4DKMT2AMEN1 | |
| SCHEMBL11427937 | 0.81 | ADRA1B (0.44) | OPRK1PDE4DKMT2AAVPR1A | |
| SCHEMBL11428325 | 0.80 | OPRK1 (0.57) | OPRK1PDE4DKMT2AHTR2CMEN1 | |
| SCHEMBL11431742 | 0.80 | OPRK1 (0.47) | OPRK1PDE4DKMT2AMEN1AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4239684-A | 1,5'-Benzodiazepine-2-ones, pharmaceutical compositions thereof and method of use thereof | KNOLL AG (DE) | 1980-12-16 | — | — | US | disclosed |
| US-RE30293-E | Process for preparing 1,5-benzodiazepine-2-ones | KNOLL A.G. (DE) | 1980-06-03 | — | — | US | disclosed |
| US-4108852-A | Process for preparing 1,5-benzodiazepine-2-ones | KNOLL AG. (DE) | 1978-08-22 | — | — | US | disclosed |