Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11446890 | 0.79 | TP53 (0.47) | PTGDR2TP53TSHRCYP3A4MAPT | |
| SCHEMBL11441403 | 0.78 | SMN1; SMN2 (0.37) | PTGDR2TSHRCYP3A4MAPTCYP2C9 | |
| SCHEMBL11437286 | 0.77 | CHRM2 (0.41) | TP53KCNH2BCHECHRM2CHRM4 | |
| SCHEMBL11450503 | 0.75 | MITF (0.39) | PTGDR2CHRM2CHRM3 | |
| SCHEMBL11334031 | 0.72 | TP53 (0.42) | PTGDR2TP53TSHRCYP3A4MAPT | |
| SCHEMBL11435695 | 0.72 | CHRM3 (0.39) | MAPTCHRM2CHRM1CHRM3 | |
| SCHEMBL11434896 | 0.69 | TP53 (0.47) | PTGDR2TP53TSHRCYP3A4MAPT | |
| SCHEMBL11446523 | 0.69 | TP53 (0.47) | PTGDR2TP53TSHRCYP3A4MAPT | |
| SCHEMBL16311866 | 0.69 | CHRM2 (0.56) | TSHRBCHECHRM2CHRM4CHRM1 | |
| SCHEMBL11438333 | 0.69 | ALDH1A1 (0.36) | PTGDR2CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4217362-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1980-08-12 | — | — | US | disclosed |
| US-4212888-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1980-07-15 | — | — | US | disclosed |
| US-4128663-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1978-12-05 | — | — | US | disclosed |