Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11437192 | 0.77 | PTGDR2 (0.43) | CHRM2CHRM4CHRM1CHRM3KCNH2 | |
| SCHEMBL11446891 | 0.77 | MEN1 (0.40) | TP53MEN1KMT2AALDH1A1OPRM1 | |
| SCHEMBL11334034 | 0.73 | MEN1 (0.39) | TP53MEN1KMT2AALDH1A1OPRM1 | |
| SCHEMBL11446647 | 0.73 | TP53 (0.48) | CHRM2CHRM3TP53MEN1KMT2A | |
| SCHEMBL11450504 | 0.73 | ALDH1A1 (0.36) | MEN1KMT2AALDH1A1OPRM1NPC1 | |
| SCHEMBL11437770 | 0.72 | ALDH1A1 (0.40) | CHRM2CHRM3MEN1KMT2ASLC18A3 | |
| SCHEMBL11435697 | 0.71 | ALDH1A1 (0.45) | CHRM2CHRM3MEN1KMT2AALDH1A1 | |
| SCHEMBL11330415 | 0.69 | KDM4E (0.48) | TP53MEN1KMT2APKMALDH1A1 | |
| SCHEMBL28277997 | 0.69 | KCNH2 (0.55) | CHRM2CHRM4CHRM1CHRM3KCNH2 | |
| SCHEMBL11438337 | 0.69 | ALDH1A1 (0.43) | CHRM2CHRM1CHRM3KCNH2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4217362-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1980-08-12 | — | — | US | disclosed |
| US-4212888-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1980-07-15 | — | — | US | disclosed |
| US-4128663-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1978-12-05 | — | — | US | disclosed |