Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 2/20 | 0.40 |
| ▸ | NOS1 | P29475 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.38 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11437225 | 0.81 | USP2 (0.39) | CA2CA1MEN1KMT2ACA12 | |
| SCHEMBL11313376 | 0.75 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1LMNAUSP2 | |
| SCHEMBL11313374 | 0.75 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1LMNAUSP2 | |
| SCHEMBL1237696 | 0.74 | TRPA1 (0.44) | CA2CA1MEN1KMT2AALDH1A1 | |
| SCHEMBL1237695 | 0.74 | TRPA1 (0.44) | CA2CA1MEN1KMT2AALDH1A1 | |
| SCHEMBL7700455 | 0.74 | LMNA (0.56) | GSK3BCA2CA1MEN1KMT2A | |
| SCHEMBL11322817 | 0.74 | HTT (0.43) | GSK3BCA2CA1MEN1KMT2A | |
| SCHEMBL11315381 | 0.74 | MEN1 (0.53) | CA2CA1MEN1KMT2AALDH1A1 | |
| SCHEMBL10340700 | 0.74 | MEN1 (0.53) | CA2CA1MEN1KMT2AALDH1A1 | |
| SCHEMBL11322821 | 0.74 | HTT (0.43) | GSK3BCA2CA1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0009865-A1 | Process for the stereoselective synthesis of the E isomer of aryl alkyl oximes | RHONE-POULENC INC. (US) | 1980-04-16 | — | — | EP | disclosed |
| US-4158015-A | Process for the stereoselective synthesis of the E isomer of aryl alkyl oximes | MOBIL OIL CORPORATION (US) | 1979-06-12 | — | — | US | disclosed |