Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11434388 | 0.93 | MAOB (0.44) | MAOBMAPTFYNCLK4DYRK1B | |
| SCHEMBL11434522 | 0.92 | CNR2 (0.43) | MAOBMAPTHPGDKMT2AL3MBTL1 | |
| SCHEMBL11429410 | 0.89 | MAPT (0.40) | MAOBMAPTFYNCLK4DYRK1B | |
| SCHEMBL11549547 | 0.86 | BRD4 (0.44) | MAOBMAPTHPGDMEN1KMT2A | |
| SCHEMBL11550515 | 0.86 | BRD4 (0.41) | MAOBHPGDMEN1KMT2AALOX15 | |
| SCHEMBL11439626 | 0.85 | ALKBH3 (0.43) | MAOBMAPTFYNCLK4DYRK1B | |
| SCHEMBL11437276 | 0.84 | ALDH1A1 (0.47) | MAOBMAPTHPGDMEN1KMT2A | |
| SCHEMBL11434477 | 0.83 | MAPT (0.45) | MAPTPGRPARP10PARP11ALOX15 | |
| SCHEMBL11175526 | 0.81 | PTPN5 (0.46) | MEN1KMT2AALOX15ALOX12KDM4E | |
| SCHEMBL11426297 | 0.80 | BRD9 (0.53) | MAOBMAPTALOX15ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4235619-A | USING 3-PHENYL-4(1H)-PYRIDONES OR PYRIDINETHIONES | ELI LILLY AND COMPANY (US) | 1980-11-25 | — | — | US | disclosed |
| US-4152136-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1979-05-01 | — | — | US | disclosed |