Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | RPA1 | P27694 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11434388 | 0.88 | MAOB (0.44) | MAPTMAOBFYNCLK4DYRK1B | |
| SCHEMBL11429789 | 0.87 | EGFR (0.44) | HSD11B1AHRMAOBALDH1A1 | |
| SCHEMBL11435056 | 0.87 | HSD11B1 (0.42) | ALKBH3HSD11B1AKR1C2AHRPOLB | |
| SCHEMBL11437271 | 0.85 | MAOB (0.43) | TP53MAPTMAOBL3MBTL1FYN | |
| SCHEMBL11439462 | 0.84 | AHR (0.38) | ALKBH3HSD11B1AHRSLC6A3MAOB | |
| SCHEMBL11434522 | 0.83 | CNR2 (0.43) | MAPTMAOBL3MBTL1ALDH1A1 | |
| SCHEMBL11434888 | 0.82 | AHR (0.41) | ALKBH3HSD11B1AKR1C2AHRMAPT | |
| SCHEMBL11428176 | 0.82 | HSD11B1 (0.45) | ALKBH3HSD11B1AKR1C2AHRMAOB | |
| SCHEMBL11436424 | 0.81 | RORB (0.44) | AKR1C2MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL11428696 | 0.81 | HSD11B1 (0.50) | HSD11B1AHRTP53MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4235619-A | USING 3-PHENYL-4(1H)-PYRIDONES OR PYRIDINETHIONES | ELI LILLY AND COMPANY (US) | 1980-11-25 | — | — | US | disclosed |
| US-4152136-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1979-05-01 | — | — | US | disclosed |