Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.40 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11434522 | 0.95 | CNR2 (0.43) | MAOBBRD9BRD7ALDH1A1MAPT | |
| SCHEMBL11437271 | 0.93 | MAOB (0.43) | MAOBALOX15ALOX12FYNCLK4 | |
| SCHEMBL11437276 | 0.91 | ALDH1A1 (0.47) | MAOBALOX15ALOX12ABCB1ALDH1A1 | |
| SCHEMBL11429410 | 0.89 | MAPT (0.40) | MAOBALOX15ALOX12FYNCLK4 | |
| SCHEMBL11439626 | 0.88 | ALKBH3 (0.43) | MAOBFYNCLK4DYRK1BALDH1A1 | |
| SCHEMBL11175526 | 0.87 | PTPN5 (0.46) | ALOX15ALOX12BRD9RAB9A | |
| SCHEMBL11428619 | 0.83 | HSD17B10 (0.46) | CA12CA9ALDH1A1CNR2 | |
| SCHEMBL11426297 | 0.82 | BRD9 (0.53) | MAOBALOX15BRD9BRD7ALDH1A1 | |
| SCHEMBL11434573 | 0.80 | BRD4 (0.40) | MAOBCLK4ALDH1A1MAPTPGR | |
| SCHEMBL11431671 | 0.80 | EGFR (0.50) | MAOBALOX15ALOX12CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152136-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1979-05-01 | — | — | US | claimed |
| US-4235619-A | USING 3-PHENYL-4(1H)-PYRIDONES OR PYRIDINETHIONES | ELI LILLY AND COMPANY (US) | 1980-11-25 | — | — | US | disclosed |
| US-4152136-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1979-05-01 | — | — | US | disclosed |