Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIMP3 | P35625 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | CD40 | P25942 | 2/20 | 0.44 |
| ▸ | CD40LG | P29965 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.40 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.40 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11432542 | 0.87 | APEX1 (0.44) | TIMP3MEN1KMT2AALDH1A1CD40 | |
| SCHEMBL11442053 | 0.87 | APEX1 (0.44) | TIMP3MEN1KMT2AALDH1A1CD40 | |
| SCHEMBL11429449 | 0.85 | TIMP3 (0.55) | TIMP3MEN1KMT2AALDH1A1USP2 | |
| SCHEMBL11432549 | 0.85 | TIMP3 (0.55) | TIMP3MEN1KMT2AALDH1A1USP2 | |
| SCHEMBL11431764 | 0.81 | TIMP3 (0.50) | TIMP3MEN1KMT2AALDH1A1USP2 | |
| SCHEMBL11636816 | 0.81 | TIMP3 (0.47) | TIMP3MEN1KMT2AALDH1A1USP2 | |
| SCHEMBL11444114 | 0.81 | TIMP3 (0.46) | TIMP3MEN1KMT2AALDH1A1USP2 | |
| SCHEMBL11444025 | 0.81 | KMT2A (0.46) | TIMP3MEN1KMT2AALDH1A1USP2 | |
| SCHEMBL11420299 | 0.81 | TIMP3 (0.58) | TIMP3MEN1KMT2AALDH1A1USP2 | |
| SCHEMBL11437960 | 0.81 | TIMP3 (0.64) | TIMP3MEN1KMT2AALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4229584-A | Ureylenebis(anionic substituted phenylene carbonyl)imino naphthalene sulfonic acids and naphthalene carboxylic acids and their salts | AMERICAN CYANAMID COMPANY (US) | 1980-10-21 | — | — | US | disclosed |
| US-4177209-A | COMPLEMENT INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1979-12-04 | — | — | US | disclosed |