Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL11437728

CCCCC(c1ccccc1)P(=O)(O)OCC.N

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.49
ACP3 P15309 2/20 0.42
MAPK1 P28482 2/20 0.42
HPGD P15428 1/20 0.42
ALOX15 P16050 1/20 0.42
TSHR P16473 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
CETP P11597 3/20 0.41
MAPT P10636 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17223172 0.89 POLB (0.53) POLBACP3MAPK1HPGDALOX15
SCHEMBL29444204 0.85 ESR1 (0.36) POLBMAPK1ALOX15TSHRCETP
SCHEMBL1246417 0.81 ACP3 (0.62) POLBACP3
SCHEMBL6664553 0.78 POLB (0.44) POLBMAPK1HPGDALOX15TSHR
SCHEMBL8348616 0.78 POLB (0.50) POLBACP3MAPK1HPGDALOX15
SCHEMBL6237835 0.76 POLB (0.59) POLBACP3MAPK1HPGDALOX15
SCHEMBL11232157 0.75 ACP3 (0.58) ACP3CETP
SCHEMBL21101801 0.75 ACP3 (0.58) ACP3CETP
SCHEMBL11297491 0.75 ACP3 (0.58) ACP3CETP
SCHEMBL8949630 0.75 GAA (0.43) POLBACP3NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4199494-A Metal complexes of α-aminophosphonic acid half-esters and of α-a CIBA-GEIGY CORPORATION (US) 1980-04-22 US disclosed